Development of novel quality control material based on CRISPR/Cas9 editing and xenografts for MLH1 protein deficiency testing
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DOI: 10.1002/jcla.23746
Abstract: Mismatch repair deficiency (dMMR) status induced by MLH1 protein deficiency plays a pivotal role in therapeutic decision‐making for cancer patients. Appropriate quality control (QC) materials are necessary for monitoring the accuracy of MLH1 protein deficiency… read more here.
Keywords: quality control; mlh1 protein; deficiency; protein deficiency ... See more keywords