Articles with "mll wdr5" as a keyword



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MLL/WDR5 Complex Regulates Kif2A Localization to Ensure Chromosome Congression and Proper Spindle Assembly during Mitosis.

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Published in 2017 at "Developmental cell"

DOI: 10.1016/j.devcel.2017.05.023

Abstract: Mixed-lineage leukemia (MLL), along with multisubunit (WDR5, RbBP5, ASH2L, and DPY30) complex catalyzes the trimethylation of H3K4, leading to gene activation. Here, we characterize a chromatin-independent role for MLL during mitosis. MLL and WDR5 localize… read more here.

Keywords: mitosis; mll complex; mll; localization ... See more keywords