Articles with "mll1 interaction" as a keyword



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Menin–MLL1 Interaction Small Molecule Inhibitors: A Potential Therapeutic Strategy for Leukemia and Cancers

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28073026

Abstract: Encoded by the MEN1 gene, menin protein is a fusion protein that is essential for the oncogenic transformation of mixed-lineage leukemia (MLL) and leads to acute leukemia (AL). Therefore, accumulating evidence has demonstrated that inhibition… read more here.

Keywords: small molecule; mll1 interaction; leukemia; menin mll1 ... See more keywords