COMPASS Ascending: Emerging clues regarding the roles of MLL3/KMT2C and MLL2/KMT2D proteins in cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.05.024
Abstract: The KMT2 (lysine methyltransferase) family of histone modifying proteins play essential roles in regulating developmental pathways, and mutations in the genes encoding these proteins have been strongly linked to many blood and solid tumor cancers.… read more here.
Keywords: mll2 kmt2d; compass ascending; mll3 kmt2c; kmt2c mll2 ... See more keywords
Abstract 366: Association of MLL2/KMT2D and MLL3/KMT2C with chronic myeloid leukemia
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DOI: 10.1158/1538-7445.am2018-366
Abstract: Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm linked to the Philadelphia chromosome presence that generates the BCR-ABL1 fusion oncogene. Tyrosine kinase inhibitors (TKI) such as imatinib mesylate (IM) dramatically improved the treatment efficiency… read more here.
Keywords: mll2 kmt2d; kmt2d mll3; kmt2d; mll3 kmt2c ... See more keywords