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Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.05.024
Abstract: The KMT2 (lysine methyltransferase) family of histone modifying proteins play essential roles in regulating developmental pathways, and mutations in the genes encoding these proteins have been strongly linked to many blood and solid tumor cancers.…
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Keywords:
mll2 kmt2d;
compass ascending;
mll3 kmt2c;
kmt2c mll2 ... See more keywords
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Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-366
Abstract: Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm linked to the Philadelphia chromosome presence that generates the BCR-ABL1 fusion oncogene. Tyrosine kinase inhibitors (TKI) such as imatinib mesylate (IM) dramatically improved the treatment efficiency…
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Keywords:
mll2 kmt2d;
kmt2d mll3;
kmt2d;
mll3 kmt2c ... See more keywords