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   Articles with "mlx" as a keyword



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Synthesis and characterization of meloxicam eutectics with mandelic acid and saccharin for enhanced solubility

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recommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2020.1775633

Abstract: Abstract Meloxicam (MLX) is a non-steroidal anti-inflammatory which is practically insoluble in water, requiring high concentrations to reach therapeutic levels and causing frequently gastrointestinal effects. In this way, the aim of this study was to… read more here.

Keywords: mlx; saccharin; enhanced solubility; mandelic acid ... See more keywords
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Combination anesthetic therapy: co-delivery of ropivacaine and meloxicam using transcriptional transactivator peptide modified nanostructured lipid carriers in vitro and in vivo

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recommendations! Published in 2022 at "Drug Delivery"

DOI: 10.1080/10717544.2021.2023695

Abstract: Abstract Combination therapy combining two drugs in one modified drug delivery system is used to achieve synergistic analgesic effect, and bring effective control of pain management, especially postoperative pain management. In the present study, a… read more here.

Keywords: transcriptional transactivator; combination; mlx; rvc mlx ... See more keywords
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Intra-articular injection PLGA blends sustained-release microspheres loaded with meloxicam: preparation, optimization, evaluation in vitro and in vivo

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recommendations! Published in 2022 at "Drug Delivery"

DOI: 10.1080/10717544.2022.2144545

Abstract: Abstract Meloxicam (MLX) is a commonly used drug in the clinical treatment of osteoarthritis, but it is associated with gastrointestinal adverse reactions. Therefore, in this study, we developed a sustained-release microsphere formulation of MLX for… read more here.

Keywords: vitro vivo; intra articular; mlx; release ... See more keywords
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Preparation and physicochemical characterization of meloxicam orally fast disintegration tablet using its solid dispersion

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recommendations! Published in 2018 at "Brazilian Journal of Pharmaceutical Sciences"

DOI: 10.1590/s2175-97902017000400176

Abstract: Meloxicam (MLX) is a non-steroidal, anti-inflammatory drug that is prescribed in the treatment of rheumatoid arthritis and osteoarthritis. MLX is practically insoluble in water and exhibits a slow onset of action. In this study, MLX… read more here.

Keywords: mlx; disintegration; water; meloxicam ... See more keywords
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Chitosan Nanoparticles for Meloxicam Ocular Delivery: Development, In Vitro Characterization, and In Vivo Evaluation in a Rabbit Eye Model

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recommendations! Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14050893

Abstract: Eye inflammation is considered one of the most common co-morbidities associated with ocular disorders and surgeries. Conventional management of this condition with non-steroidal anti-inflammatory drugs as eye drops is associated with low corneal bioavailability and… read more here.

Keywords: vitro; ocular delivery; mlx; chitosan nanoparticles ... See more keywords