Mitomycin C-loaded PTMC15–F127–PTMC15 hydrogel maintained better bleb function after filtering glaucoma surgery in monkeys with intraocular hypertension
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DOI: 10.1039/d3ra01002c
Abstract: There is an unmet need for a safer and more effective approach for antimetabolite application to prevent bleb fibrosis after glaucoma filtering surgery. Here, we utilized our previously developed thermosensitive sustained-release agent, mitomycin C-loaded poly(trimethylene… read more here.
Keywords: glaucoma; hydrogel; surgery; mmc hydrogel ... See more keywords
Assessment of the efficacy of repeated instillations of mitomycin C mixed with a thermosensitive hydrogel in an orthotopic rat bladder cancer model
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DOI: 10.1177/1756287218762064
Abstract: Background: We investigated a thermoreversible hydrogel that is highly viscous at body temperature, while fluid-like at a low temperature, thus aiming for a slow and prolonged intravesical drug release. Our study purposed to assess antitumor… read more here.
Keywords: hydrogel; hydrogel orthotopic; efficacy; model ... See more keywords