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   Articles with "mmp expression" as a keyword



Interleukin‐11/gp130 upregulates MMP‐13 expression and cell migration in OSCC by activating PI3K/Akt and AP‐1 signaling

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recommendations! Published in 2022 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30902

Abstract: Oral squamous cell carcinoma (OSCC) is an extremely common head and neck cancer with a poor 5‐year survival rate, especially in cases of metastatic disease. Interleukin (IL)‐11 reportedly promotes cell growth and the epithelial–mesenchymal transition… read more here.

Keywords: metastasis; cell; migration oscc; mmp expression ... See more keywords
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PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.

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recommendations! Published in 2021 at "Cancer letters"

DOI: 10.1016/j.canlet.2021.04.014

Abstract: Invasion of bladder cancer (BC) cells from the mucosa into the muscle layer is canonical for BC progression while phospholipase D isoform 1 (PLD1) is known to mediate development of cancer through phosphatidic acid (PA)… read more here.

Keywords: invasion; mmp expression; pld1; tumor invasion ... See more keywords

The role of urine derived exosome metalloproteinases as biomarkers for prostate cancer detection may be confounded by non-malignant prostatic inflammation

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-23767-5

Abstract: Matrix metalloproteinases (MMPs) are emerging as promising diagnostic and prognostic biomarkers for prostate cancer (PCa). This study explored the association between urinary exosome MMP levels and the incidence of prostate cancer. Urine samples were collected… read more here.

Keywords: cancer; prostate cancer; biomarkers prostate; biopsy ... See more keywords

Epigenetic regulation of MMP-11 and -16 expression in human prostate cancer: the role of KDM6A.

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recommendations! Published in 2025 at "Epigenomics"

DOI: 10.1080/17501911.2025.2586858

Abstract: AIMS Matrix metalloproteinases (MMPs) promote prostate cancer (PCa) progression by degrading the extracellular matrix and enhancing metastasis. PCa is considered an "epigenetic catastrophe" due to disrupted histone modifications caused by chromatin-modifying enzyme dysregulation. We previously… read more here.

Keywords: mmp; prostate cancer; pca; mmp expression ... See more keywords

Trimetazidine suppresses oxidative stress, inhibits MMP‐2 and MMP‐9 expression, and prevents cardiac rupture in mice with myocardial infarction

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recommendations! Published in 2018 at "Cardiovascular Therapeutics"

DOI: 10.1111/1755-5922.12460

Abstract: BACKGROUND/AIMS Cardiac rupture (CR) is a catastrophic complication of acute myocardial infarction (MI). At present, there are no effective pharmacological strategies for preventing post-MI rupture. Here we investigated the effect of trimetazidine (TMZ) on post-MI… read more here.

Keywords: mmp mmp; mmp expression; rupture; oxidative stress ... See more keywords

Steroid receptor coactivator 1 promotes human hepatocellular carcinoma invasiveness through enhancing MMP‐9

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recommendations! Published in 2024 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.18171

Abstract: SRC‐1 functions as a transcriptional coactivator for steroid receptors and various transcriptional factors. Notably, SRC‐1 has been implicated in oncogenic roles in multiple cancers, including breast cancer and prostate cancer. Previous investigations from our laboratory… read more here.

Keywords: expression; coactivator; mmp expression; hcc metastasis ... See more keywords

Dihydrocaffeic Acid Prevents UVB-Induced Oxidative Stress Leading to the Inhibition of Apoptosis and MMP-1 Expression via p38 Signaling Pathway

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recommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2019/2419096

Abstract: Chronic UVB exposure promotes oxidative stress, directly causes molecular damage, and induces aging-related signal transduction, leading to skin photoaging. Dihydrocaffeic acid (DHCA) is a phenolic compound with potential antioxidant capacity and is thus a promising… read more here.

Keywords: mmp expression; acid; uvb induced; oxidative stress ... See more keywords

Expression of Matrix Metalloproteinase-7 Predicts Poor Prognosis in Gastric Cancer

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recommendations! Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/2300979

Abstract: To date, no potential markers have been established for predicting prognosis in gastric cancer. Matrix metalloproteinase-7 (MMP-7) has been suggested as a prognostic marker in several cancers. In this study, we aimed to determine the… read more here.

Keywords: prognosis gastric; mmp expression; gastric cancer; expression ... See more keywords
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Abstract 1579: Matrix metalloproteinase 1: Oncogene or tumor suppressor in ovarian cancer

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recommendations! Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.am2020-1579

Abstract: Purpose: The high risk of tumor recurrence and subsequent development of chemotherapy resistance plays a major role in the high mortality rate for high grade serous ovarian cancer (OC) patients. To investigate genes contributing to… read more here.

Keywords: matrix metalloproteinase; mmp expression; expression; ovarian cancer ... See more keywords

Pam3CSK4 Induces MMP-9 Expression in Human Monocytic THP-1 Cells

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recommendations! Published in 2017 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000475298

Abstract: Background: Matrix metalloproteinase (MMP)-9 is known to degrade the extracellular matrix and increased MMP-9 levels are related with the pathogenesis of many inflammatory conditions including obesity. Pam3CSK4 is a synthetic triacylated lipopeptide (LP) which is… read more here.

Keywords: pam3csk4; mmp expression; thp; thp cells ... See more keywords

Prognostic value of matrix metalloproteinase-2 protein and matrix metalloproteinase-9 protein in colorectal cancer: a meta-analysis

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recommendations! Published in 2024 at "BMC Cancer"

DOI: 10.1186/s12885-024-12775-9

Abstract: Matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) are critical components of the extracellular matrix (ECM) in colorectal cancer (CRC). We aimed to evaluate the prognostic value of MMP-2 and MMP-9 in patients with CRC. We… read more here.

Keywords: mmp; cancer; mmp expression; matrix metalloproteinase ... See more keywords