Interleukin‐11/gp130 upregulates MMP‐13 expression and cell migration in OSCC by activating PI3K/Akt and AP‐1 signaling
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30902
Abstract: Oral squamous cell carcinoma (OSCC) is an extremely common head and neck cancer with a poor 5‐year survival rate, especially in cases of metastatic disease. Interleukin (IL)‐11 reportedly promotes cell growth and the epithelial–mesenchymal transition… read more here.
Keywords: metastasis; cell; migration oscc; mmp expression ... See more keywords
PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer letters"
DOI: 10.1016/j.canlet.2021.04.014
Abstract: Invasion of bladder cancer (BC) cells from the mucosa into the muscle layer is canonical for BC progression while phospholipase D isoform 1 (PLD1) is known to mediate development of cancer through phosphatidic acid (PA)… read more here.
Keywords: invasion; mmp expression; pld1; tumor invasion ... See more keywords
Trimetazidine suppresses oxidative stress, inhibits MMP‐2 and MMP‐9 expression, and prevents cardiac rupture in mice with myocardial infarction
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Therapeutics"
DOI: 10.1111/1755-5922.12460
Abstract: BACKGROUND/AIMS Cardiac rupture (CR) is a catastrophic complication of acute myocardial infarction (MI). At present, there are no effective pharmacological strategies for preventing post-MI rupture. Here we investigated the effect of trimetazidine (TMZ) on post-MI… read more here.
Keywords: mmp mmp; mmp expression; rupture; oxidative stress ... See more keywords
Dihydrocaffeic Acid Prevents UVB-Induced Oxidative Stress Leading to the Inhibition of Apoptosis and MMP-1 Expression via p38 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/2419096
Abstract: Chronic UVB exposure promotes oxidative stress, directly causes molecular damage, and induces aging-related signal transduction, leading to skin photoaging. Dihydrocaffeic acid (DHCA) is a phenolic compound with potential antioxidant capacity and is thus a promising… read more here.
Keywords: mmp expression; acid; uvb induced; oxidative stress ... See more keywords
Expression of Matrix Metalloproteinase-7 Predicts Poor Prognosis in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/2300979
Abstract: To date, no potential markers have been established for predicting prognosis in gastric cancer. Matrix metalloproteinase-7 (MMP-7) has been suggested as a prognostic marker in several cancers. In this study, we aimed to determine the… read more here.
Keywords: prognosis gastric; mmp expression; gastric cancer; expression ... See more keywords
Abstract 1579: Matrix metalloproteinase 1: Oncogene or tumor suppressor in ovarian cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-1579
Abstract: Purpose: The high risk of tumor recurrence and subsequent development of chemotherapy resistance plays a major role in the high mortality rate for high grade serous ovarian cancer (OC) patients. To investigate genes contributing to… read more here.
Keywords: matrix metalloproteinase; mmp expression; expression; ovarian cancer ... See more keywords
Pam3CSK4 Induces MMP-9 Expression in Human Monocytic THP-1 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000475298
Abstract: Background: Matrix metalloproteinase (MMP)-9 is known to degrade the extracellular matrix and increased MMP-9 levels are related with the pathogenesis of many inflammatory conditions including obesity. Pam3CSK4 is a synthetic triacylated lipopeptide (LP) which is… read more here.
Keywords: pam3csk4; mmp expression; thp; thp cells ... See more keywords
The flavonoid hesperidin exerts anti-photoaging effect by downregulating matrix metalloproteinase (MMP)-9 expression via mitogen activated protein kinase (MAPK)-dependent signaling pathways
Sign Up to like & getrecommendations! Published in 2018 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-017-2058-8
Abstract: BackgroundHesperidin is a flavonoid with antioxidant, anti-inflammatory, and immune modulatory activities. Photoaging is a consequence of chronic exposure to the sun and ultraviolet (UV) radiation. This study was designed to evaluate the efficacy of hesperidin… read more here.
Keywords: uvb treated; mmp expression; anti photoaging; hesperidin ... See more keywords
Ceramide induces MMP-9 expression through JAK2/STAT3 pathway in airway epithelium
Sign Up to like & getrecommendations! Published in 2020 at "Lipids in Health and Disease"
DOI: 10.1186/s12944-020-01373-w
Abstract: Background Ceramide, a bioactive lipid, plays an essential role in the development of several pulmonary inflammatory diseases. Matrix metallopeptidase 9 (MMP-9) regulates the synthesis and degradation of extracellular matrix, and is associated with airway remodeling… read more here.
Keywords: jak2 stat3; mmp expression; ceramide; expression ... See more keywords
MMP-11 promoted the oral cancer migration and FAK/Src activation
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.15824
Abstract: Matrix metalloproteinase-11 (MMP-11) has been observed in most invasive human carcinomas. The current study investigated the association between the clinicopathological characteristics and MMP-11 expression in oral squamous cell carcinoma (OSCC) patients. Immunohistochemistry (IHC) staining was… read more here.
Keywords: mmp expression; fak src; mmp; migration ... See more keywords
Over-expression of mir-124 inhibits MMP-9 expression and decreases invasion of renal cell carcinoma cells.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201810_16041
Abstract: OBJECTIVE JAK-STAT3 signaling pathway is related to tumor invasion and metastasis that can regulate matrix metalloproteinase-9 (MMP-9) expression. MicroRNA-124 (MiR-124) was found downregulated in renal cell carcinoma. Bioinformatics analysis revealed the complementary binding site between… read more here.
Keywords: invasion; mmp expression; stat3; expression ... See more keywords