Associations of MMP-2 and MMP-9 gene polymorphism with ulinastatin efficacy in patients with severe acute pancreatitis
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DOI: 10.1042/bsr20160612
Abstract: We aim to explore the associations between matrix metalloproteinase (MMP) MMP-2/MMP-9 gene polymorphism with ulinastatin (UTI) efficacy in treating severe acute pancreatitis (SAP). A total of 276 SAP patients were assigned into the control (n=135)… read more here.
Keywords: mmp mmp; efficacy; mmp gene; patients mmp ... See more keywords
The association between MMP-1 gene rs1799750 polymorphism and knee osteoarthritis risk
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20181257
Abstract: Matrix metalloproteinase 1 (MMP-1) degrades cartilage, which may result in osteoarthritis (OA) development. Several studies have explored the association between MMP-1 gene rs1799750 polymorphism and OA in different populations. However, the results are inconsistent. The… read more here.
Keywords: gene rs1799750; mmp gene; rs1799750 polymorphism; association mmp ... See more keywords
Association of functional MMP-2 gene variant with intracranial aneurysms: case-control genetic association study and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Neurosurgery"
DOI: 10.1080/02688697.2018.1427213
Abstract: Abstract Introduction: Abnormalities in Matrix Metalloproteinase (MMP) genes, which are important in extracellular matrix (ECM) maintenance and therefore arterial wall integrity are a plausible underlying mechanism of intracranial aneurysm (IA) formation, growth and subsequent rupture.… read more here.
Keywords: analysis; mmp; association; functional mmp ... See more keywords
The MMP-1 Gene rs1799750 Polymorphism Is Associated with Breast Cancer Risk.
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DOI: 10.1089/gtmb.2021.0016
Abstract: Numerous studies investigating an association between the matrix metalloproteinase-1 (MMP-1) gene rs1799750 polymorphism and breast cancer (BC) risk have reported inconsistent results. Therefore, this meta-analysis was undertaken to obtain a more precise estimate of the… read more here.
Keywords: risk; gene rs1799750; breast cancer; mmp gene ... See more keywords
MMP-3 gene polymorphisms are associated with increased risk of osteoarthritis in Chinese men
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DOI: 10.18632/oncotarget.18493
Abstract: Osteoarthritis (OA) is the most common late-onset degenerative joint disease., It is characterized by progressive degradation of articular cartilage. We investigated the association between OA occurrence and single nucleotide polymorphisms (SNPs) in the matrix metalloproteinase-3… read more here.
Keywords: dominant 038; 038 dominant; increased risk; associated increased ... See more keywords
Does the functional polymorphism-1562C/T of MMP-9 gene influence brain disorders?
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1110967
Abstract: Metalloproteinase-9 (MMP-9) is one of the most strongly expressed matrix metalloproteinases (MMPs) in the brain. The MMP-9 activity in the brain is strictly regulated, and any disruptions in this regulation contribute to a development of… read more here.
Keywords: mmp; brain; mmp gene; functional polymorphism ... See more keywords