Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2018.01.002
Abstract: Membrane type-1 matrix metalloproteinase (MT1-MMP) is a transmembrane MMP which triggers intracellular signaling and regulates extracellular matrix proteolysis, two functions that are critical for tumor-associated angiogenesis and inflammation. While green tea catechins, particularly epigallocatechin gallate… read more here.
Keywords: green tea; tea catechins; mt1 mmp; mmp ... See more keywords
Tetracycline Analogs Inhibit Osteoclast Differentiation by Suppressing MMP-9-Mediated Histone H3 Cleavage
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DOI: 10.3390/ijms20164038
Abstract: Osteoporosis is a common disorder of bone remodeling, caused by the imbalance between bone resorption by osteoclasts and bone formation by osteoblasts. Recently, we reported that matrix metalloproteinase-9 (MMP-9)-dependent histone H3 proteolysis is a key… read more here.
Keywords: cleavage; mediated histone; mmp; tetracycline analogs ... See more keywords