Role of oxidative stress in epigenetic modification of MMP-9 promoter in the development of diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2017 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-017-3594-0
Abstract: BackgroundIn the pathogenesis of diabetic retinopathy, damaged retinal mitochondria accelerate apoptosis of retinal capillary cells, and regulation of oxidative stress by manipulating mitochondrial superoxide dismutase (SOD2) protects mitochondrial homeostasis and prevents the development of diabetic… read more here.
Keywords: mmp promoter; diabetic retinopathy; mmp; oxidative stress ... See more keywords
Orthodontic force regulates metalloproteinase-3 promoter in osteoblasts and transgenic mouse models
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DOI: 10.1016/j.jds.2021.11.015
Abstract: Background/purpose Previously we demonstrated up-regulation of matrix metalloproteinase-3 (MMP-3) in human osteoblasts under compression and in bony specimens of experimental orthodontic tooth movement (OTM). Here, we studied the temporal characteristics of compression stimulation in human… read more here.
Keywords: mmp promoter; mouse; transgenic mouse; force ... See more keywords
miRNA-584-3p inhibits gastric cancer progression by repressing Yin Yang 1- facilitated MMP-14 expression
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DOI: 10.1038/s41598-017-09271-5
Abstract: Recent evidence shows the emerging roles of promoter-targeting endogenous microRNAs (miRNAs) in regulating gene transcription. However, miRNAs affecting the transcription of matrix metalloproteinase 14 (MMP-14) in gastric cancer remain unknown. Herein, through integrative mining of… read more here.
Keywords: mir 584; gastric cancer; facilitated mmp; mmp promoter ... See more keywords