Gallbladder cancer-associated genetic variants rs1003349 and rs1004030 regulate MMP14 expression by altering SOX10 and MYB binding sites.
Sign Up to like & getrecommendations! Published in 2023 at "Human molecular genetics"
DOI: 10.1093/hmg/ddad077
Abstract: The pathogenesis of gallbladder cancer is complex, involving environmental and genetic risk factors. The matrix metallopeptidase 14 (MMP14) alters the tumor microenvironment and promotes tumorigenesis. In this study, we have characterized the role of the… read more here.
Keywords: mmp14; expression; mmp14 expression; rs1004030 rs1003049 ... See more keywords
Overexpression of MMP14 predicts the poor prognosis in gastric cancer
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000026545
Abstract: Abstract Background: Plenty of studies have showed matrix metalloproteinase 14 (MMP14) expression might be associated with the prognosis of gastric cancer (GC). However, no definite conclusion has been obtained for the contradictory results. Methods: We… read more here.
Keywords: expression; prognosis gastric; mmp14 expression; cancer ... See more keywords