LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "mmp2" as a keyword



Photo from wikipedia

Post-transcriptional regulation of MMP2 mRNA by its interaction with miR-20a and Nucleolin in breast cancer cell lines.

Sign Up to like & get
recommendations! Published in 2021 at "Molecular biology reports"

DOI: 10.1007/s11033-021-06261-9

Abstract: Matrix-metalloproteinase-2 (MMP2) is a foremost MMP, governing invasion of breast cancer cells during metastasis. miR-20a was reported to induce mesenchymal to epithelial transition in MDA-MB-231 cells and its endogenous expression varies directly with invasiveness of… read more here.

Keywords: mir 20a; mmp2; post transcriptional; breast cancer ... See more keywords

Mating induces production of MMP2 in the llama oviduct: Analysis of MMP2 effect on semen.

Sign Up to like & get
recommendations! Published in 2018 at "Animal reproduction science"

DOI: 10.1016/j.anireprosci.2018.03.016

Abstract: Ovulation of South American Camelids is induced by mating. After copulation, sperm are stored into the oviduct to be released near ovulation time. To study whether copulation induces matrix metalloproteinase-2 (MMP2) secretion in the oviduct,… read more here.

Keywords: mmp2; copulation; effect semen; mmp2 effect ... See more keywords

PAD1 promotes epithelial-mesenchymal transition and metastasis in triple-negative breast cancer cells by regulating MEK1-ERK1/2-MMP2 signaling.

Sign Up to like & get
recommendations! Published in 2017 at "Cancer letters"

DOI: 10.1016/j.canlet.2017.08.019

Abstract: Peptidylargininedeiminase 1 (PAD1) catalyzes protein for citrullination, and this activity has been linked to the epidermal cornification. However, a role for PAD1 in tumorigenesis, including breast cancers has not been previously explored. Here we first… read more here.

Keywords: mmp2; breast; breast cancer; pad1 ... See more keywords

YY1 inhibits the migration and invasion of pancreatic ductal adenocarcinoma by downregulating the FER/STAT3/MMP2 signaling pathway.

Sign Up to like & get
recommendations! Published in 2019 at "Cancer letters"

DOI: 10.1016/j.canlet.2019.07.019

Abstract: Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis and a high mortality rate. The transcription factor YY1 acts as an inhibitor of many types of tumors. We found that YY1 knockdown promoted the invasion and… read more here.

Keywords: mmp2; invasion; migration; cancer ... See more keywords

Long noncoding RNA HOTAIR functions as ceRNA to regulate MMP2 in paraquat induced lung epithelial-mesenchymal transition.

Sign Up to like & get
recommendations! Published in 2021 at "Toxicology"

DOI: 10.1016/j.tox.2021.152891

Abstract: Paraquat (PQ) poisoning induces epithelial-mesenchymal transition (EMT) in the lungs, resulting in pulmonary fibrosis with a poor prognosis. Although competitive endogenous RNA (ceRNA) networks are known to exert post-transcriptional regulatory effects, the roles of such… read more here.

Keywords: mmp2; hotair; rna; mir ... See more keywords

Trophoblast survival signaling during human placentation requires HSP70 activation of MMP2-mediated HBEGF shedding

Sign Up to like & get
recommendations! Published in 2017 at "Cell Death and Differentiation"

DOI: 10.1038/cdd.2017.104

Abstract: Survival of trophoblast cells in the low oxygen environment of human placentation requires metalloproteinase-mediated shedding of HBEGF and downstream signaling. A matrix metalloproteinase (MMP) antibody array and quantitative RT-PCR revealed upregulation of MMP2 post-transcriptionally in… read more here.

Keywords: mmp2; hbegf shedding; human placentation; trophoblast survival ... See more keywords

Glycosaminoglycans influence enzyme activity of MMP2 and MMP2/TIMP3 complex formation - Insights at cellular and molecular level

Sign Up to like & get
recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-41355-2

Abstract: The extracellular matrix (ECM) is a highly dynamic network constantly remodeled by a fine-tuned protein formation and degradation balance. Matrix metalloproteinases (MMPs) constitute key orchestrators of ECM degradation. Their activity is controlled by tissue inhibitors… read more here.

Keywords: timp3 complex; mmp2; formation; timp3 ... See more keywords

Naringin dihydrochalcone potentially binds to catalytic domain of matrix metalloproteinase-2: molecular docking, MM-GBSA, and molecular dynamics simulation approach

Sign Up to like & get
recommendations! Published in 2022 at "Natural Product Research"

DOI: 10.1080/14786419.2022.2118746

Abstract: Abstract Matrix metalloproteinase-2 (MMP2), an extracellular matrix remodulating protein’s increased activity causes cancer-metastasis. Potential MMP2 inhibitors showed sever side-effects in clinical trials. Present study is focused on identification natural MMP2 inhibitor by applying molecular docking,… read more here.

Keywords: molecular docking; mmp2; catalytic domain; docking gbsa ... See more keywords

Bone marrow stromal cell antigen 2(BST2) suppresses the migration and invasion of trophoblasts in preeclampsia by downregulating matrix metallopeptidase 2(MMP2)

Sign Up to like & get
recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2074712

Abstract: ABSTRACT Preeclampsia is a grievous pregnancy-related complication with an incidence of approximately 5∼7% in pregnant women. Placental abnormalities and decreased placental perfusion associated with impaired trophoblast invasion are early pathological findings of preeclampsia. BST2 is… read more here.

Keywords: migration invasion; bst2; mmp2; expression ... See more keywords

P02.24.B THE IMPACT OF THE IDH1 R132H MUTATION ON MMP2 METHYLATION, EXPRESSION AND INVASION IN EXPERIMENTAL GLIOMAS AND HUMAN GBMS

Sign Up to like & get
recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae144.127

Abstract: Glioblastoma (GBM) is a highly diffusive tumor which restricts the efficacy of surgical resection and facilitates tumor recurrence. Matrix metalloproteinase 2 (MMP2) is the extracellular matrix protease that is activated by MMP14 expressed by microglia… read more here.

Keywords: methylation; experimental gliomas; mmp2; tumor ... See more keywords

ANGI-15. IDH1 R132H MUTATION IMPAIRS GLIOMA INVASIVENESS THROUGH EPIGENETIC REPRESSION OF MMP2 IN EXPERIMENTAL MODELS AND HUMAN GBMS

Sign Up to like & get
recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.0081

Abstract: Glioblastoma (GBM) is a highly diffusive tumor which restricts the efficacy of surgical resection and facilitates tumor recurrence. Matrix metalloproteinase 2 (MMP2) is the extracellular matrix protease that is activated by MMP14 expressed by microglia… read more here.

Keywords: mmp2 expression; mmp2; tumor; mutation ... See more keywords