ANGI-15. IDH1 R132H MUTATION IMPAIRS GLIOMA INVASIVENESS THROUGH EPIGENETIC REPRESSION OF MMP2 IN EXPERIMENTAL MODELS AND HUMAN GBMS
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.0081
Abstract: Glioblastoma (GBM) is a highly diffusive tumor which restricts the efficacy of surgical resection and facilitates tumor recurrence. Matrix metalloproteinase 2 (MMP2) is the extracellular matrix protease that is activated by MMP14 expressed by microglia… read more here.
Keywords: mmp2 expression; mmp2; tumor; mutation ... See more keywords
Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis
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DOI: 10.1186/s12890-020-01317-1
Abstract: Background Matrix metalloproteinase 2 (MMP2) has been found to be related to malignant tumors; the aim of this study was to investigate the correlation between MMP2 expression in lung cancer tissues and clinical parameters of… read more here.
Keywords: cancer; mmp2 expression; lung cancer;
G6PD facilitates clear cell renal cell carcinoma invasion by enhancing MMP2 expression through ROS-MAPK axis pathway
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Oncology"
DOI: 10.3892/ijo.2020.5041
Abstract: Glucose-6-phosphate dehydrogenase (G6PD) is crucial rate-limiting enzyme of the pentose phosphate pathway (PPP). G6PD dysregulation has been reported in various types of human cancer, and the role of G6PD in cancer progression was demonstrated in… read more here.
Keywords: g6pd; mmp2 expression; invasion; cell ... See more keywords