Association of MMP1 and MMP3 haplotypes with myocardial infarction and echocardiographic parameters of the left ventricle
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2022
Abstract: Myocardial infarction (MI) leads to ischemia and afterward to left ventricular (LV) remodeling. Matrix metalloproteinase−1 (MMP1) and −3 (MMP3) belong to the family of endopeptidases and together they can dissolve most of the components of the… read more here.
Keywords: mmp3; myocardial infarction; echocardiographic parameters; mmp1 mmp3 ... See more keywords
Simultaneous determination of CXCL7 chemokine and MMP3 metalloproteinase as biomarkers for rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122705
Abstract: This paper reports the preparation of the first dual electrochemical immunosensor for the simultaneous determination of the CXCL7 chemokine and the MMP3 metalloproteinase as relevant biomarkers for the better diagnosis and monitoring of rheumatoid arthritis… read more here.
Keywords: simultaneous determination; determination; mmp3; cxcl7 chemokine ... See more keywords
Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101221
Abstract: Highlights • MMP3 is upregulated in colon cancers.• Tumor cell-associated MMP3 expression is important for tumor growth.• The cancer therapy by MMP3 inhibition is improved together with oncolytic virus.• Downregulation of MMP3 reduces tumor cell… read more here.
Keywords: oncolytic virus; mmp3; therapy; targeting matrix ... See more keywords
Matrix metalloproteinases (MMP) 3 and 9 as biomarkers of severity in COVID-19 patients
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-021-04677-8
Abstract: The molecular basis of the wide clinical heterogeneity of Coronavirus disease 2019 (COVID-19) is still unknown. Matrix metalloproteinases (MMPs) may have a role in the lung damage and regeneration that occur in severe patients. We… read more here.
Keywords: matrix metalloproteinases; severity covid; covid patients; mmp3 ... See more keywords
CircSEC24A (hsa_circ_0003528) interference suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells via miR-421/MMP3 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2057761
Abstract: Accumulating evidence indicates that circular RNAs (circRNAs) function as conclusive modulators in diverse tumors, including in hepatocellular carcinoma (HCC). Nonetheless, knowledge of the latent mechanisms involving circRNAs in HCC development is insufficient. circSEC24A (hsa_circ_0003528) was… read more here.
Keywords: hepatocellular carcinoma; circsec24a; hcc; mmp3 ... See more keywords
CCAAT/Enhancer Binding Protein β-Mediated MMP3 Upregulation Promotes Esophageal Squamous Cell Cancer Invasion In Vitro and Is Associated with Metastasis in Human Patients.
Sign Up to like & getrecommendations! Published in 2019 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2018.0291
Abstract: Aims: Metastasis is a significant obstacle to curing esophageal squamous cell carcinoma (ESCC). The CCAAT/enhancer binding protein β (C/EBPβ) and matrix metalloproteinase 3 (MMP3) are thought to play key roles in cancer invasion and metastasis.… read more here.
Keywords: protein; esophageal squamous; invasion; mmp3 ... See more keywords
Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia
Sign Up to like & getrecommendations! Published in 2018 at "Disease Markers"
DOI: 10.1155/2018/1371425
Abstract: Background Metalloproteinases (MMPs) play a pivotal role during the process of trophoblast invasion and placentation. The appearance of five functional single-nucleotide polymorphisms (SNP) in the genes of the metalloproteinases most commonly implicated in the implantation… read more here.
Keywords: mmp2; mmp9; mmp1; preeclampsia ... See more keywords
Increase in Blood-Brain Barrier (BBB) Permeability Is Regulated by MMP3 via the ERK Signaling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/6655122
Abstract: Background The blood-brain barrier (BBB) regulates the exchange of molecules between the brain and peripheral blood and is composed primarily of microvascular endothelial cells (BMVECs), which form the lining of cerebral blood vessels and are… read more here.
Keywords: bbb permeability; blood brain; mmp3; blood ... See more keywords
Abstract 552: Bradykinin Receptor B1/ Matrix Metalloprotease 3 Pathway is a Novel Target in Preventing Cardiac Ischemia-reperfusion Injury
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DOI: 10.1161/res.127.suppl_1.552
Abstract: Introduction: Impaired endothelial function leads to the progression of heart failure after Ischemia-reperfusion (IR). Kinin activation of bradykinin receptor 1 (B1R), a G protein-coupled receptor that has been found to induce capillary leakage, may serve… read more here.
Keywords: receptor; mmp3; mice; antagonist ... See more keywords
Susceptibility of MMP3 gene polymorphism to coronary artery disease: A meta-analysis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Biochemistry"
DOI: 10.5937/jomb0-43315
Abstract: Background: Conclusions on susceptibility of MMP3 -1612 5A/6A to morbid risk of coronary artery disease (CAD) are controversial. This meta-analysis aims to obtain the accurate relationship between them. Methods: Relevant literatures on susceptibility of MMP3… read more here.
Keywords: susceptibility mmp3; mmp3 1612; mmp3; susceptibility ... See more keywords
Matrix Metalloproteinase 3: a Novel Effective Biomarker for Predicting the Mortality and the Severity of Pneumonia.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical laboratory"
DOI: 10.7754/clin.lab.2021.210404
Abstract: BACKGROUND Matrix metalloproteinase 3 (MMP3) is known as an inflammatory factor; however, the effectiveness of MMP3 for diagnosis of pneumonia and predicting outcomes is unclear. We evaluated the diagnostic and prognostic value of serum MMP3… read more here.
Keywords: pneumonia; auc; patients pneumonia; mmp3 ... See more keywords