SREBP1 promotes the invasion of colorectal cancer accompanied upregulation of MMP7 expression and NF-κB pathway activation
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DOI: 10.1186/s12885-019-5904-x
Abstract: BackgroundSterol-regulatory element binding protein 1 (SREBP1), an intracellular cholesterol sensor located in the endoplasmic reticulum, regulates the intracellular cholesterol by the Insig-Srebp-Scap pathway. Over-expression of SREBP1 can cause dyslipidemia. SREBP1 can regulate the metabolic pathway,… read more here.
Keywords: colorectal cancer; srebp1; expression; mmp7 expression ... See more keywords