Matrix Metalloproteinases 9 Contributes to Inflammatory Responses in Helicobacter pylori-Positive Gastric Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.70000
Abstract: Helicobacter pylori-induced inflammatory microenvironment plays a pivotal role in the development of gastric cancer (GC). This study investigates whether matrix metallopeptidase 9 (MMP9) mediates H. pylori-induced effects in GC progression. GC patients were stratified on… read more here.
Keywords: mmp9; gastric cancer; pylori positive; helicobacter pylori ... See more keywords
MicroRNA‐212 promotes the recovery function and vascular regeneration of endothelial progenitor cells in mice with ischemic stroke through inactivation of the notch signaling pathway via downregulating MMP9 expression
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27463
Abstract: Ischemic stroke is a refractory disease caused by cerebral ischemic injury, which results in brain dysfunction. This study intends to investigate the effects of microRNA‐212 (miR‐212) on the recovery function and vascular regeneration of endothelial… read more here.
Keywords: ischemic stroke; vascular regeneration; mmp9; recovery function ... See more keywords
27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2017.02.001
Abstract: Breast carcinoma plays a vital role in the reasons of global women's death. ER-related invasion and migration play an important part in the development and prognosis of breast cancer. Here, we found that 27-Hydroxycholesterol (27HC)… read more here.
Keywords: mmp9; breast; invasion; invasion migration ... See more keywords
High Glucose Activates ERK1/2 to Stabilize AP1 and Increase MMP9 Expression in Diabetic Foot Ulcers.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112550
Abstract: Increased matrix metalloproteinase 9 (MMP9) expression is involved in delayed wound healing in diabetic foot ulcers. We created skin wounds in normal SD rats and STZ-induced diabetic SD rats, then we found protein levels of… read more here.
Keywords: high glucose; mmp9 expression; mmp9; increase mmp9 ... See more keywords
Transcriptomic profiling of feline teeth highlights the role of matrix metalloproteinase 9 (MMP9) in tooth resorption
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-75998-3
Abstract: Tooth resorption (TR) in domestic cats is a common and painful disease characterised by the loss of mineralised tissues from the tooth. Due to its progressive nature and unclear aetiology the only treatment currently available… read more here.
Keywords: tooth resorption; metalloproteinase mmp9; mmp9; matrix metalloproteinase ... See more keywords
Combined knockdown of CD151 and MMP9 may inhibit the malignant biological behaviours of triple-negative breast cancer through the GSK-3β/β-catenin-related pathway
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-71533-w
Abstract: Triple-negative breast cancer (TNBC) represents a significant health concern for women worldwide, and the overproduction of MMP9 and CD151 is associated with various cancers, influencing tumour growth and progression. This study aimed to investigate how… read more here.
Keywords: mmp9; breast cancer; cd151 mmp9; negative breast ... See more keywords
Causal associations of MICB, CTSA, and MMP9 proteins with oral cancer: Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-77042-0
Abstract: Oral cancer (ORCA) is the most prevalent histological subtype of oral malignancies in which immune modulation is relevant. The goal of this work was to employ Mendelian randomization (MR) to investigate the causal connection between… read more here.
Keywords: mmp9; micb ctsa; ctsa mmp9; mendelian randomization ... See more keywords
Inhibition of matrix metalloproteinase-9 attenuates kidney fibrosis and cellular senescence in the transition from acute kidney injury to chronic kidney disease
Sign Up to like & getrecommendations! Published in 2025 at "Renal Failure"
DOI: 10.1080/0886022x.2025.2499897
Abstract: Abstract Background The mechanisms underlying the progression of chronic kidney disease (CKD) following acute kidney injury (AKI) remain poorly understood. Senescent cells induce maladaptive repair have been identified as a significant contributor to CKD subsequent… read more here.
Keywords: senescence; mmp9; cellular senescence; fibrosis ... See more keywords
Zoobiquity experiments show the importance of the local MMP9-plasminogen axis in inflammatory bowel diseases in both dogs and patients.
Sign Up to like & getrecommendations! Published in 2023 at "International immunology"
DOI: 10.1093/intimm/dxad006
Abstract: Using a zoobiquity concept, we directly connect animal phenotypes to a human disease mechanism: the reduction of local plasminogen levels caused by matrix metalloproteinase-9 (MMP9) activity is associated with the development of inflammation in the… read more here.
Keywords: zoobiquity; disease; inflammatory bowel; plasminogen ... See more keywords
Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through &bgr;-catenin signaling
Sign Up to like & getrecommendations! Published in 2017 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfw076
Abstract: Background. For patients using peritoneal dialysis (PD), the peritoneal membrane can develop fibrosis and angiogenesis, leading to ultrafiltration failure, chronic hypervolemia and increased risk of technique failure and mortality. Matrix metalloproteinases (MMPs), and specifically the… read more here.
Keywords: peritoneal membrane; bgr catenin; mmp9;
Trypanosoma cruzi Induces the PARP1/AP-1 Pathway for Upregulation of Metalloproteinases and Transforming Growth Factor β in Macrophages: Role in Cardiac Fibroblast Differentiation and Fibrosis in Chagas Disease
Sign Up to like & getrecommendations! Published in 2020 at "mBio"
DOI: 10.1128/mbio.01853-20
Abstract: Cardiomyopathy is the most important clinical manifestation of T. cruzi-driven CD. Recent studies have suggested the detrimental role of the matrix metalloproteinases MMP2 and MMP9 in extracellular matrix (ECM) degradation during cardiac remodeling in T.… read more here.
Keywords: role; differentiation; mmp9; parp1 ... See more keywords