Ktx-1029, a Potent, Selective MMSET/NSD2 Inhibitor Is Effective in t(4;14) Multiple Myeloma Preclinical Models
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DOI: 10.1182/blood-2024-198468
Abstract: Background: A translocation event between chromosome 4 (MMSET/NSD2 gene) and chromosome 14 (immunoglobulin heavy chain [IgH] locus) (t(4;14)) is a primary, clonal event in 15-20% of newly diagnosed multiple myeloma (MM) patients that is associated… read more here.
Keywords: bortezomib; ktx; mmset; cell ... See more keywords