MnBr2-Catalyzed Direct and Site-Selective Alkylation of Indoles and Benzo[h]quinoline.
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DOI: 10.1021/acs.orglett.0c01398
Abstract: Manganese-catalyzed regioselective C-H alkylation of indoles and benzo[h]quinoline with a variety of unactivated alkyl iodides is reported. Unlike other Mn-catalyzed C-H functionalization, this protocol does not require a Grignard reagent base and employs a simple… read more here.
Keywords: benzo quinoline; mnbr2 catalyzed; alkylation indoles; indoles benzo ... See more keywords