Modulatory effect of Tagetes erecta flowers essential oils via Nrf2/HO-1/NF-κB/p65 axis mediated suppression of N-methyl-Nʹnitro-N-nitroguanidine (MNNG) induced gastric cancer in rats
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DOI: 10.1007/s11010-020-04005-0
Abstract: Protective effect of Tagetes erecta flowers essential oils was investigated on oxidative stress, immune response, inflammation, and apoptosis against N -methyl- N ʹnitro- N -nitroguanidine (MNNG) induced gastric cancer in rats. Essential oil were extracted… read more here.
Keywords: gastric cancer; tagetes erecta; mnng induced; cancer ... See more keywords
Ursolic and oleanolic acids suppress MNNG induced malignant transformation of human gastric mucosal epithelium by regulating the PI3 K/AKT pathway
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DOI: 10.1038/s41598-025-03606-3
Abstract: Berberine hydrochloride (Ber) is the primary active compound in the traditional Chinese medicine ‘Huanglian’. Ursolic acid (UA) and oleanolic acid (OA) are the main triterpenoids extracted from ‘Tengligen’. Notably, both Ber and UA/OA exhibit antitumour… read more here.
Keywords: induced malignant; malignant transformation; mnng induced; pathway ... See more keywords