A scalable and safe continuous flow procedure for in-line generation of diazomethane and its precursor MNU
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DOI: 10.1039/c6gc03066a
Abstract: Diazomethane is a valuable C1-building block for organic synthesis. Due to its intrinsic reactivity and instability, handling of this reagent is associated with serious safety hazards. Herein we present a simple and robust continuous flow… read more here.
Keywords: diazomethane; scalable safe; continuous flow; generation diazomethane ... See more keywords
Abstract 5255: Comparison of high-fructose and standard diets in methylnitrosourea (MNU)-induced ER+mammary cancers: Altered carcinogenesis, differential effects of metformin, and metabolomic differences
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DOI: 10.1158/1538-7445.am2017-5255
Abstract: The MNU-induced model of ER+ mammary cancers in Sprague-Dawley rats has routinely been employed in screening for chemopreventive agents. We recently reported that metformin was ineffective in preventing mammary cancers in rats on a standard… read more here.
Keywords: mammary cancers; vehicle; high fructose; mnu ... See more keywords
The reason for the amelioration of N-methyl-N-nitrosourea-induced retinitis pigmentosa in rats by hydrogen-rich saline.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2017.10.03
Abstract: AIM To investigate the effects of hydrogen-rich saline (HRS) on microglia activation and Sirtuin type 1 (Sirt1) in rats with N-methyl-N-nitrosourea (MNU)-induced retinitis pigmentosa (RP). METHODS Rats were divided into norm (N) group, model (M)… read more here.
Keywords: rich saline; mnu induced; group; hydrogen rich ... See more keywords
The regeneration-responsive element careg monitors activation of Müller glia after MNU-induced damage of photoreceptors in the zebrafish retina
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2023.1160707
Abstract: In contrast to mammals, zebrafish can regenerate their damaged photoreceptors. This capacity depends on the intrinsic plasticity of Müller glia (MG). Here, we identified that the transgenic reporter careg, a marker of regenerating fin and… read more here.
Keywords: mnu; ller glia; careg; retina ... See more keywords