Articles with "mnx1" as a keyword



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LncRNA MNX1‐AS1 promotes the progression of cervical cancer through activating MAPK pathway

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27712

Abstract: Long noncoding RNAs (lncRNAs) have been discovered as significant regulators in a wide range of human cancers. Among them, lncRNA MNX1‐AS1 has been proved to be an oncogene in ovarian cancer and glioblastoma. However, the… read more here.

Keywords: mnx1; mnx1 as1; cervical cancer; lncrna mnx1 ... See more keywords
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3144 – ECTOPIC EXPRESSION OF THE HOMEOBOX GENE MNX1 IS THE TRANSFORMING EVENT IN A MOUSE MODEL OF PEDIATRIC T(7;12)(Q36;P13) PEDIATRIC ACUTE MYELOID LEUKEMIA

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Published in 2020 at "Experimental Hematology"

DOI: 10.1016/j.exphem.2020.09.151

Abstract: Pediatric acute myeloid leukemia (AML) with the translocation t(7;12)(q36;p13) is a form of childhood leukemia associated with inferior outcome. In the current investigation we have studied the gene alterations that are induced by this chromosomal… read more here.

Keywords: leukemia; ectopic expression; gene; mnx1 etv6 ... See more keywords
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Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet.

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Published in 2021 at "Stem cell research"

DOI: 10.1016/j.scr.2021.102522

Abstract: MNX1 encodes a homeobox transcription factor with conserved embryonic requirements in spinal motor neuron formation and pancreatic beta-cell differentiation. Mutations in MNX1 are associated with dominantly inherited Currarino syndrome and neonatal diabetes. To better understand… read more here.

Keywords: line expressing; line; generation hipsc; mnx1 ... See more keywords
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Clinical significance of long noncoding RNA MNX1-AS1 in human cancers: a meta-analysis of cohort studies and bioinformatics analysis based on TCGA datasets

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Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1888596

Abstract: ABSTRACT MNX1-AS1 expression has been proposed to be abnormally upregulated in multiple human malignancies and be linked with the survival outcome of patients. However, relevant conclusions were yielded based on the limited samples. Therefore, we… read more here.

Keywords: mnx1 as1; bioinformatics analysis; mnx1; cohort studies ... See more keywords
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Increased Expression of microRNA-141-3p Improves Necrotizing Enterocolitis of Neonates Through Targeting MNX1

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Published in 2020 at "Frontiers in Pediatrics"

DOI: 10.3389/fped.2020.00385

Abstract: Objective: MicroRNA-141-3p (miR-141-3p) has been investigated in various kinds of cancers. This research delves into the functions and regulatory mechanisms of miR-141-3p in necrotizing enterocolitis (NEC) of neonates. Methods: NEC tissues were obtained from neonatal… read more here.

Keywords: microrna 141; mir 141; necrotizing enterocolitis; mnx1 ... See more keywords