Direct enantioseparation of mandelic acid by high-performance liquid chromatography using a phenyl column precoated with a small amount of cyclodextrin additive in a mobile phase.
Sign Up to like & getrecommendations! Published in 2020 at "Chirality"
DOI: 10.1002/chir.23228
Abstract: Direct enantioseparation of mandelic acid by high-performance liquid chromatography (HPLC) with a reversed phase column and a mobile phase containing a small amount of hydroxylpropyl-β-cyclodextrin (HP-β-CD) was studied as an efficient method for saving consumption… read more here.
Keywords: phenyl column; column; mandelic acid; direct enantioseparation ... See more keywords
Enantioseparation of basic drugs by reverse phase high-performance liquid chromatography system using carboxymethyl-β-cyclodextrin as chiral mobile phase additive.
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23470
Abstract: A rapid and efficient method was developed for enantioseparation of basic drugs, using carboxymethyl-β-cyclodextrin (CM-β-CD) as chiral mobile phase additive, rather than involving costly chiral column in high-performance liquid chromatography (HPLC) system. Four of the… read more here.
Keywords: enantioseparation basic; phase; mobile phase; using carboxymethyl ... See more keywords
Separation of structurally related primary aliphatic amines using hydrophilic interaction chromatography with fluorescence detection after postcolumn derivatization with o-phthaldialdehyde/mercaptoethanol.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201701005
Abstract: The retention behavior of primary aliphatic amines (homologous series of aliphatic alkyl amines and cycloalkyl amines) and positional isomers of alkylamines in the hydrophilic interaction chromatography mode was studied. The study was carried out on… read more here.
Keywords: detection; primary aliphatic; hydrophilic interaction; aliphatic amines ... See more keywords
Isocratic micellar liquid chromatography using mixed anionic and non-ionic surfactants as mobile phase additives for separation of 17 free amino acids
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DOI: 10.1007/s11696-019-00791-0
Abstract: In this work, an isocratic micellar chromatographic method for separation of 17 free amino acids was first established. Mixed anionic and non-ionic surfactants were used as mobile phase additives. Besides, a chromatographic environment was simulated… read more here.
Keywords: phase; amino acids; separation; isocratic micellar ... See more keywords
Relation between char structures and formation of volatiles during the pyrolysis of Shenfu coal: Further understanding on the effects of mobile phase and fixed phase
Sign Up to like & getrecommendations! Published in 2018 at "Fuel Processing Technology"
DOI: 10.1016/j.fuproc.2018.07.022
Abstract: Abstract The formation of resultant volatiles is closely related with chemical structure of char during the pyrolysis process. In this study, all-components, that are semi-char, tar and gas product obtained by Shenfu coal pyrolyzed under… read more here.
Keywords: tar; mobile phase; shenfu coal; formation ... See more keywords
Simultaneous optimization of mobile phase composition and pH using retention modeling and experimental design
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.07.054
Abstract: HIGHLIGHTSA new 3 dimensional design with 18 input runs was presented to model mobile phase influence on the chromatographic selectivity, as a function of gradient time (tG), pH and ternary eluent composition (tC).DryLab4 (U)HPLC method… read more here.
Keywords: phase; mobile phase; method; composition ... See more keywords
Ceftriaxone pharmacokinetics by a sensitive and simple LC-MS/MS method: Development and application.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113484
Abstract: Ceftriaxone is a third-generation cephalosporin, worldwide use as a first-line treatment for several infections, including life-threatening infections as meningitis or endocarditis. Nowadays, ceftriaxone use is changing, embracing high-dose schemes, new populations treated and requirement of… read more here.
Keywords: method; pharmacokinetics sensitive; ceftriaxone pharmacokinetics; ceftriaxone ... See more keywords
Development of an Eco-friendly HPLC method for the simultaneous determination of three benzodiazepines using green mobile phase
Sign Up to like & getrecommendations! Published in 2019 at "Microchemical Journal"
DOI: 10.1016/j.microc.2018.10.059
Abstract: Abstract The analysis of the class of benzodiazepines (BDZs) is of a great importance on the levels of forensic, clinical and pharmaceutical uses. The study is focusing on the separation of three BDZs which are… read more here.
Keywords: mobile phase; eco friendly; using green; hplc method ... See more keywords
Modeling an in silico platform to predict chromatographic profiles of UV filters using ChromSimulator
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DOI: 10.1016/j.microc.2020.105002
Abstract: Abstract The use of Analytical Quality by Design (AQbD) concepts is increasing for rational development of analytical methods of liquid chromatography. To facilitate the use of the AQbD approach, we developed an in silico tool… read more here.
Keywords: modeling silico; predict chromatographic; silico platform; platform ... See more keywords
Supercritical fluid chromatographic separation on preparative scale and in continuous mode
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Supercritical Fluids"
DOI: 10.1016/j.supflu.2017.12.027
Abstract: Abstract Chromatography with supercritical fluids (SFC) is a powerful tool for carrying out separations of substances with very similar structure and volatility, such as isomers of various kinds. In this contribution, we discuss the separation… read more here.
Keywords: separation process; process; separation; mobile phase ... See more keywords
Simultaneous Preconcentration, Identification, and Quantitation of Selenoamino Acids in Oils by Enantioselective High Performance Liquid Chromatography and Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b02089
Abstract: Selenium is an essential micronutrient for humans. In food, selenium can be present in both inorganic and organic forms, the latter mainly being selenomethionine, Se-methyl-selenocysteine, and selenocystine. Selenoamino acid speciation rarely involves the chirality of… read more here.
Keywords: mobile phase; selenoamino; selenoamino acids; preconcentration ... See more keywords