Mobilization of hematopoietic stem cells with lenograstim in multiple myeloma patients: Prospective multicenter observational study (KMM122)
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DOI: 10.1002/cam4.5657
Abstract: Current guidelines recommend using filgrastim or tbo‐filgrastim to mobilize hematopoietic progenitor cells in an autologous setting. However, previous studies have suggested other forms of granulocyte colony‐stimulating factor (G‐CSF) are equally efficacious, possibly with fewer leukaphereses… read more here.
Keywords: myeloma patients; mobilization hematopoietic; multiple myeloma; hematopoietic stem ... See more keywords
Innate Immunity and Mobilization of Hematopoietic Stem Cells
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DOI: 10.1007/s40778-017-0087-3
Abstract: Purpose of ReviewSeveral mechanisms have been postulated to orchestrate mobilization of hematopoietic stem/progenitor cells (HSPCs), and still more work is needed to better understand this process and to gain better mechanistic insight.Recent FindingsEvidence accumulated that… read more here.
Keywords: mobilization; hematopoietic stem; mobilization hematopoietic; stem ... See more keywords
Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells
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DOI: 10.1038/s41375-018-0122-0
Abstract: Pharmacological mobilization of hematopoietic stem progenitor cells (HSPCs) from bone marrow (BM) into peripheral blood (PB) is a result of mobilizing agent-induced “sterile inflammation” in the BM microenvironment due to complement cascade (ComC) activation. Here… read more here.
Keywords: progenitor cells; stem progenitor; mobilization; hematopoietic stem ... See more keywords
Plerixafor and granulocyte‐colony‐stimulating factor for mobilization of hematopoietic stem cells for autologous transplantation in Chinese patients with non−Hodgkin's lymphoma: a randomized Phase 3 study
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DOI: 10.1111/trf.14426
Abstract: This Phase 3 randomized, double‐blind study evaluated the efficacy and safety of plerixafor plus granulocyte‐colony‐stimulating factor for the mobilization of hematopoietic stem cells in Chinese patients with non−Hodgkin's lymphoma. read more here.
Keywords: stimulating factor; colony stimulating; hematopoietic stem; mobilization hematopoietic ... See more keywords