Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects
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DOI: 10.1007/s00213-017-4650-5
Abstract: Rationale3,4-Methylenedioxymethamphetamine (MDMA) is used recreationally and investigated as an adjunct to psychotherapy. Methylphenidate and modafinil are psychostimulants that are used to treat attention-deficit/hyperactivity disorder and narcolepsy, respectively, but they are also misused as cognitive enhancers.… read more here.
Keywords: effects mdma; methylphenidate modafinil; modafinil; endocrine ... See more keywords
Involvement of nitric oxide pathway in the anti-inflammatory effect of modafinil on indomethacin-, stress-, and ethanol -induced gastric mucosal injury in rat
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DOI: 10.1016/j.ejphar.2020.173579
Abstract: Gastric ulcer is a prevalent disease with various etiologies, including non-steroidal anti-inflammatory drugs (NSAIDs), stress conditions, and alcohol, resulting in an inflammatory condition in the gastric mucosa. The aim of this study was to explore… read more here.
Keywords: anti inflammatory; modafinil; stress; indomethacin ... See more keywords
How effective are pharmaceuticals for cognitive enhancement in healthy adults? A series of meta-analyses of cognitive performance during acute administration of modafinil, methylphenidate and D-amphetamine
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DOI: 10.1016/j.euroneuro.2020.07.002
Abstract: Modafinil, methyphenidate (MPH) and d-amphetamine (d-amph) are putative cognitive enhancers. However, efficacy of cognitive enhancement has yet to be fully established. We examined cognitive performance in healthy non-sleep-deprived adults following modafinil, MPH, or d-amph vs… read more here.
Keywords: meta analyses; mph; cognitive performance; modafinil ... See more keywords
Rapid identification of the “smart drug” modafinil in suspicious tablets by DART-HRMS combined with micropunching
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DOI: 10.1039/c9ay02624j
Abstract: Recently, increasing numbers of imported parcels have contained tablets that have been mixed with others containing modafinil; thus, it is necessary to develop a rapid screening method for this compound. A rapid and accurate approach… read more here.
Keywords: modafinil; combined micropunching; dart hrms; hrms combined ... See more keywords
Pharmacokinetic and pharmacodynamic of the cognitive enhancer modafinil: Relevant clinical and forensic aspects
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DOI: 10.1080/08897077.2019.1700584
Abstract: Abstract Modafinil is a nonamphetamine nootropic drug with an increasingly therapeutic interest due to its different sites of action and behavioral effects in comparison to cocaine or amphetamine. A review of modafinil (and of its… read more here.
Keywords: clinical forensic; cognitive enhancer; forensic aspects; modafinil ... See more keywords
Identification of adrafinil and its main metabolite modafinil in human hair. Self-administration study and interpretation of an authentic case
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DOI: 10.1080/20961790.2019.1704482
Abstract: Abstract For several years, the misuse of stimulant substances is increasingly observed both in the field of sport, to improve the functions of the body and therefore to be more performant, and also by non-athletes… read more here.
Keywords: authentic case; administration; adrafinil; hair ... See more keywords
0025 Effects of NLS-4 (Lauflumide) and modafinil in a rat model of circadian rhythm and chronic severe fatigue
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DOI: 10.1093/sleep/zsad077.0025
Abstract: The chronic fatigue syndrome (CFS) is a heterogeneous disorder characterized by easy fatigability, feverishness, diffuse pains, and depression. Many COVID-19 patients expressed a long-term effect of coronavirus (long-COVID), with some characteristics typically found in CFS.… read more here.
Keywords: period; activity; fatigue procedure; modafinil ... See more keywords
1020 Modafinil Induced Psychosis
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DOI: 10.1093/sleep/zsad077.1020
Abstract: Modafinil has been used for the treatment of numerous different conditions, including daytime somnolence (EDS). Modafinil is a non-amphetamine central nervous system (CNS) stimulant with wakefulness-promoting properties. There have been few reported cases of psychosis… read more here.
Keywords: evaluation; psychosis; induced psychosis; modafinil induced ... See more keywords
Oral modafinil facilitates intracranial self-stimulation in rats: comparison with methylphenidate
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DOI: 10.1097/fbp.0000000000000288
Abstract: Modafinil is a low-potency inhibitor of dopamine transporters (DAT) approved clinically to promote wakefulness. In most procedures used for abuse-liability assessment, modafinil produces effects similar to those of abused DAT inhibitors such as cocaine and… read more here.
Keywords: intracranial self; self stimulation; stimulation; modafinil ... See more keywords
The unique psychostimulant profile of (±)‐modafinil: investigation of behavioral and neurochemical effects in mice
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DOI: 10.1111/ejn.13376
Abstract: Blockade of dopamine (DA) reuptake via the dopamine transporter (DAT) is a primary mechanism identified as underlying the therapeutic actions of (±)‐modafinil (modafinil) and its R‐enantiomer, armodafinil. Herein, we explored the neurochemical and behavioral actions… read more here.
Keywords: psychostimulant; modafinil; cocaine; subjective effects ... See more keywords
Infant Exposure to Armodafinil Through Human Milk Following Maternal Use of Modafinil
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DOI: 10.1177/08903344221134273
Abstract: Introduction Narcolepsy, a condition adversely affecting psychological, social, and cognitive function, is more prevalent in females of childbearing age than the general population. Modafinil and armodafinil are central nervous system stimulants approved for treatment of… read more here.
Keywords: infant exposure; human milk; modafinil; infant ... See more keywords