Mechanistic modeling, simulation, and optimization of mixed‐mode chromatography for an antibody polishing step
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DOI: 10.1002/btpr.3316
Abstract: Mixed‐mode chromatography combines features of ion‐exchange chromatography and hydrophobic interaction chromatography and is increasingly used in antibody purification. As a replacement for flow‐through operations on traditional unmixed resins or as a pH‐controlled bind‐and‐elute step, the… read more here.
Keywords: step; mode chromatography; process; mixed mode ... See more keywords