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Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00084
Abstract: Cardiac troponin is a regulatory protein complex located on the sarcomere that regulates the engagement of myosin on actin filaments. Low-molecular weight modulators of troponin that bind allosterically with the calcium ion have the potential…
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Keywords:
thermodynamic model;
activation cardiac;
structural thermodynamic;
troponin ... See more keywords
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Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc04057a
Abstract: The synthesis of the electrophilic phosphonium cation (EPC) salt [C10H6(CF3)PF(C6F5)2][B(C6F5)4] 4 was achieved via oxidation of phosphine [C10H6(CF3)P(C6F5)2] 2 with XeF2 to form phosphorane [C10H6(CF3)PF2(C6F5)2] 3 and subsequent fluoride ion abstraction. Structural and spectroscopic characterization…
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Keywords:
phosphonium;
cf3;
c6f5;
electrophilic phosphonium ... See more keywords