Articles with "model acute" as a keyword



Bioenergetic dysfunction in a zebrafish model of acute hyperammonemic decompensation

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Published in 2019 at "Experimental Neurology"

DOI: 10.1016/j.expneurol.2019.01.008

Abstract: &NA; Acute hyperammonemic encephalopathy is a life‐threatening manifestation of individuals with urea cycle disorders, which is associated with high mortality rates and severe neurological sequelae in survivors. Cerebral bioenergetic failure has been proposed as one… read more here.

Keywords: hyperammonemia; dysfunction; zebrafish model; model acute ... See more keywords
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Arrhythmia susceptibility in a rat model of acute atrial dilation.

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Published in 2020 at "Progress in biophysics and molecular biology"

DOI: 10.1016/j.pbiomolbio.2019.08.012

Abstract: Atrial fibrillation (AF) is the most common cardiac arrhythmia, associated with an increased risk of stroke and heart failure. Acute AF occurs in response to sudden increases of atrial hemodynamic load, leading to atrial stretch.… read more here.

Keywords: susceptibility; dilation; model acute; model ... See more keywords

Intramuscular dimethyl trisulfide: efficacy in a large swine model of acute severe cyanide toxicity

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Published in 2019 at "Clinical Toxicology"

DOI: 10.1080/15563650.2018.1511800

Abstract: Abstract Background: Cyanide is a deadly compound used as a terrorist agent. Current FDA approved antidotes require intravenous administration, limiting their utility in a mass casualty scenario. Dimethyl trisulfide (DMTS), a sulfur-based molecule, binds cyanide… read more here.

Keywords: dmts; cyanide toxicity; swine model; model acute ... See more keywords

Transient disruption of functional connectivity and depression of neural fluctuations in a mouse model of acute septic encephalopathy.

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Published in 2022 at "Cerebral cortex"

DOI: 10.1093/cercor/bhac291

Abstract: Septic encephalopathy leads to major and costly burdens for a large percentage of admitted hospital patients. Elderly patients are at an increased risk, especially those with dementia. Current treatments are aimed at sedation to combat… read more here.

Keywords: septic encephalopathy; model acute; neural fluctuations; functional connectivity ... See more keywords

Cardioprotective microRNAs (protectomiRs) in a pig model of acute myocardial infarction and cardioprotection by ischaemic conditioning: MiR‐450a

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Published in 2024 at "British Journal of Pharmacology"

DOI: 10.1111/bph.17313

Abstract: Cardioprotective miRNAs (protectomiRs) are promising therapeutic tools. Here, we aimed to identify protectomiRs in a translational porcine model of acute myocardial infarction (AMI) and to validate their cardiocytoprotective effect. read more here.

Keywords: cardioprotective micrornas; acute myocardial; myocardial infarction; model acute ... See more keywords

Predictive Model of Acute Rectal Toxicity in Prostate Cancer Treated With Radiotherapy

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Published in 2025 at "JCO Clinical Cancer Informatics"

DOI: 10.1200/cci-24-00252

Abstract: PURPOSE To aid personalized treatment selection, we developed a predictive model for acute rectal toxicity in patients with prostate cancer undergoing radiotherapy with photons and protons. MATERIALS AND METHODS We analyzed a prospective multi-institutional cohort… read more here.

Keywords: cancer; model acute; rectal toxicity; predictive model ... See more keywords

An Experimental Model of Acute Pulmonary Damage Induced by the Phospholipase A2-Rich Venom of the Snake Pseudechis papuanus

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Published in 2025 at "Toxins"

DOI: 10.3390/toxins17060302

Abstract: An experimental model of acute pulmonary damage was developed based on the intravenous injection of the phospholipase A2 (PLA2)-rich venom of Pseudechis papuanus (Papuan black snake) in mice. Venom caused pulmonary edema, with the accumulation… read more here.

Keywords: acute pulmonary; model acute; pulmonary damage; experimental model ... See more keywords