MK-801 Treatment of Oligodendrocytes as a Cellular Model of Aging.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0471-7_32
Abstract: Cardiovascular-related accidents such as stroke are currently ranked as the second leading cause of death worldwide, and the risk of stroke increases dramatically with age. Aging results in structural and functional alterations of the oligodendrocytes… read more here.
Keywords: model aging; cellular model; treatment; 801 treatment ... See more keywords
Hypoxia extends lifespan and neurological function in a mouse model of aging
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DOI: 10.1371/journal.pbio.3002117
Abstract: There is widespread interest in identifying interventions that extend healthy lifespan. Chronic continuous hypoxia delays the onset of replicative senescence in cultured cells and extends lifespan in yeast, nematodes, and fruit flies. Here, we asked… read more here.
Keywords: chronic continuous; hypoxia; model aging; extends lifespan ... See more keywords
Genome Sequencing Variations in the Octodon degus, an Unconventional Natural Model of Aging and Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.894994
Abstract: The degu (Octodon degus) is a diurnal long-lived rodent that can spontaneously develop molecular and behavioral changes that mirror those seen in human aging. With age some degu, but not all individuals, develop cognitive decline… read more here.
Keywords: aging alzheimer; genome sequencing; disease; alzheimer disease ... See more keywords