Prophylactic benefits of systemically delivered simvastatin treatment in a house dust mite challenged murine model of allergic asthma
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14140
Abstract: Systemically delivered statins can blunt airway inflammation in ovalbumin‐challenged mice. However, in asthma clinical trials the beneficial effects of introducing oral statins are not compelling. We have invetigated this discrepancy using a clinically relevant murine… read more here.
Keywords: prophylactic benefits; model allergic; murine model; systemically delivered ... See more keywords
Distinct effects of different adjuvants in the mouse model of allergic airway inflammation.
Sign Up to like & getrecommendations! Published in 2020 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-301219-0729
Abstract: BACKGROUND Allergic asthma was typically considered as an inflammatory disease mediated by type 2 immunity. However, recent studies revealed that asthma is a complex disease displaying a variety of phenotypes and endotypes. OBJECTIVE We examined… read more here.
Keywords: different adjuvants; mouse model; model allergic; group ... See more keywords
Nicotine, as a novel tolerogenic adjuvant, enhances the efficacy of immunotherapy in a mouse model of allergic asthma
Sign Up to like & getrecommendations! Published in 2019 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.263555
Abstract: An increasing trend in the incidence of allergic diseases including asthma and related morbidity and mortality is observed worldwide during the last decades. Allergen-specific immunotherapy is suggested for the treatment of some allergic diseases; nevertheless,… read more here.
Keywords: tolerogenic adjuvant; mouse model; allergic asthma; model allergic ... See more keywords