Targeting glial cannabinoid CB2 receptors to delay the progression of the pathological phenotype in TDP‐43 (A315T) transgenic mice, a model of amyotrophic lateral sclerosis
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DOI: 10.1111/bph.14216
Abstract: Cannabinoid CB2 receptors are up‐regulated in reactive microglia in the spinal cord of TDP‐43 (A315T) transgenic mice, an experimental model of amyotrophic lateral sclerosis. To determine whether this up‐regulation can be exploited pharmacologically, we investigated… read more here.
Keywords: cb2 receptors; a315t transgenic; model amyotrophic; cannabinoid cb2 ... See more keywords
Effects of Intraoperative Vagal Nerve Stimulation on the Gastrointestinal Microbiome in a Mouse Model of Amyotrophic Lateral Sclerosis.
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DOI: 10.30802/aalas-cm-18-000039
Abstract: The gastrointestinal microbiota (GM) plays a fundamental role in health and disease and contributes to the bidirectional signaling between the gastrointestinal system and brain. The direct line of communication between these organ systems is through… read more here.
Keywords: nerve stimulation; stimulation; vagal nerve; model amyotrophic ... See more keywords