Development of Hydrogen Sulfide-Releasing Carbonic Anhydrases IX- and XII-Selective Inhibitors with Enhanced Antihyperalgesic Action in a Rat Model of Arthritis
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DOI: 10.1021/acs.jmedchem.2c00982
Abstract: An effective therapeutic approach based on the anti-inflammatory action of hydrogen sulfide (H2S) and inhibition of carbonic anhydrases (CAs) IX and XII is proposed here for the management of arthritis. H2S is a human gasotransmitter… read more here.
Keywords: carbonic anhydrases; arthritis; enhanced antihyperalgesic; rat model ... See more keywords
Evaluation of Antiarthritic and Antinociceptive Effects of Cedrol in a Rat Model of Arthritis
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DOI: 10.1155/2022/4943965
Abstract: Pharmacological studies revealed that cedrol, a natural sesquiterpene, has antioxidant, anti-inflammatory, and analgesic properties. This study is aimed at evaluating the potential antiarthritic activity of cedrol in a rat experimental model of arthritis induced by… read more here.
Keywords: arthritis; cedrol rat; cedrol; model arthritis ... See more keywords