Model‐assisted process characterization and validation for a continuous two‐column protein A capture process
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DOI: 10.1002/bit.26849
Abstract: In this study we introduce three process characterization approaches toward validation of continuous twin‐column capture chromatography (CaptureSMB), referred to as “standard,” “model assisted,” and “hybrid.” They are all based on a traditional risk‐based approach, using… read more here.
Keywords: column; validation; process; model ... See more keywords
Efficient Optimization of Process Strategies with Model-Assisted Design of Experiments.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0191-4_13
Abstract: Conventional design of experiments (DoE) methods require expert knowledge about the investigated factors and their boundary values and mostly lead to multiple rounds of time-consuming and costly experiments. The combination of DoE with mathematical process… read more here.
Keywords: design experiments; process; efficient optimization; model assisted ... See more keywords
Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD
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DOI: 10.15252/msb.20167422
Abstract: To elucidate the molecular mechanisms underlying non‐alcoholic fatty liver disease (NAFLD), we recruited 86 subjects with varying degrees of hepatic steatosis (HS). We obtained experimental data on lipoprotein fluxes and used these individual measurements as… read more here.
Keywords: metabolism; gsh; model; nad glutathione ... See more keywords
Model-Assisted Online Optimization of Gain-Scheduled PID Control Using NSGA-II Iterative Genetic Algorithm
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DOI: 10.3390/app13116444
Abstract: In the practical control of nonlinear valve systems, PID control, as a model-free method, continues to play a crucial role thanks to its simple structure and performance-oriented tuning process. To improve the control performance, advanced… read more here.
Keywords: pid control; control; gain scheduled; model assisted ... See more keywords
A retrospective comparison of the conventional versus three-dimensional printed model-assisted surgery in the treatment of acetabular fractures.
Sign Up to like & getrecommendations! Published in 2020 at "Acta orthopaedica et traumatologica turcica"
DOI: 10.5152/j.aott.2020.19054
Abstract: OBJECTIVE The aim of this study was to compare the clinical and radiological outcomes of the conventional versus individualized three-dimensional (3D) printing model-assisted pre-contoured plate fixation in the treatment of patients with acetabular fractures. METHODS… read more here.
Keywords: acetabular fractures; surgery; group; model ... See more keywords