Atrial myofibroblast activation and connective tissue formation in a porcine model of atrial fibrillation and reduced left ventricular function
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.05.025
Abstract: Aims: Atrial fibrillation (AF) is associated with fibrosis that slows electrical conduction and causes perpetuation of the arrhythmia. The molecular characterization of AF pathophysiology may provide novel therapeutic options. This study was designed to elucidate… read more here.
Keywords: atrial fibrillation; model atrial; myofibroblast activation; porcine model ... See more keywords
CREM-transgene mice: An animal model of atrial fibrillation and thrombogenesis.
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DOI: 10.1016/j.thromres.2017.07.033
Abstract: BACKGROUND The molecular pathomechanisms underlying atrial thrombogenesis are multifactorial and still require detailed investigations. Transgenic mice with cardiomyocyte-directed expression of the transcriptional repressor CREM-IbΔC-X (CREM-TG) represent an experimental model of atrial fibrillation (AF) that shows… read more here.
Keywords: thrombogenesis; model atrial; crem; atrial fibrillation ... See more keywords