Articles with "model busulfan" as a keyword



A Population Pharmacokinetics Model of Busulfan in Pediatric Patients with Thalas-semia Major.

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Published in 2025 at "Current drug metabolism"

DOI: 10.2174/0113892002402673251003055700

Abstract: Purpose: This research aimed to establish a population pharmacokinetic (PPK) model for busulfan (Bu) in Chinese pediatric patients with thalassemia major. We analyzed pharmacokinetic (PK) parameter variability and explored potential covariates affecting Bu disposition using… read more here.

Keywords: model busulfan; ppk model; pediatric patients; population ... See more keywords