Evidence for exon shuffling is sensitive to model choice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of bioinformatics and computational biology"
DOI: 10.1142/s0219720021400138
Abstract: The exon shuffling theory posits that intronic recombination creates new domain combinations, facilitating the evolution of novel protein function. This theory predicts that introns will be preferentially situated near domain boundaries. Many studies have sought… read more here.
Keywords: model; evidence exon; exon shuffling; model choice ... See more keywords
Plane inclinations: A critique of hypothesis and model choice in Barbi et al
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DOI: 10.1371/journal.pbio.3000048
Abstract: This study highlights how the mortality plateau in Barbi and colleagues can be generated by low-frequency, randomly distributed age-misreporting errors. Furthermore, sensitivity of the late-life mortality plateau in Barbi and colleagues to the particular age… read more here.
Keywords: choice barbi; hypothesis; model choice; barbi ... See more keywords