Gradient‐dependent release of the model drug TRITC‐dextran from FITC‐labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2016.09.016
Abstract: Graphical abstract Figure. No Caption available. Abstract Hair follicle research is currently focused on the development of drug‐loaded nanocarriers for the targeting of follicular structures in the treatment of skin and hair follicle‐related disorders. In… read more here.
Keywords: drug; model drug; fitc labeled; tritc dextran ... See more keywords
Proof of concept of a predictive model of drug release from long-acting implants obtained by fused-deposition modeling.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121663
Abstract: In the pharmaceutical field, there is a growing interest in manufacturing of drug delivery dosage forms adapted to the needs of a large variety of patients. 3D printing has proven to be a powerful tool… read more here.
Keywords: drug; deposition modeling; geometry; fused deposition ... See more keywords
Application of volumetric absorptive microsampling device for quantification of tacrolimus in human blood as a model drug of high blood cell partition
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.05.050
Abstract: &NA; Volumetric absorptive microsampling device (VAMS) was evaluated for bioanalysis of tacrolimus, which was used as a model drug with high blood cell partition. Aliquots of blood (ca. 10 &mgr;L) with different hematocrits and fortified… read more here.
Keywords: absorptive microsampling; volumetric absorptive; model drug; blood ... See more keywords
Analysis of pH and salt concentration on structural and model-drug delivery properties of polysaccharide-based multilayered films
Sign Up to like & getrecommendations! Published in 2019 at "Thin Solid Films"
DOI: 10.1016/j.tsf.2019.06.039
Abstract: Abstract This paper explores the influence of pH and ionic strength of polyelectrolyte solutions as a simple and chemically amenable strategy for tuning the structure and drug delivery properties of polyelectrolyte multilayers produced via layer-by-layer… read more here.
Keywords: model drug; delivery properties; drug; multilayered films ... See more keywords
QDπ: A Quantum Deep Potential Interaction Model for Drug Discovery.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.2c01172
Abstract: We report QDπ-v1.0 for modeling the internal energy of drug molecules containing H, C, N, and O atoms. The QDπ model is in the form of a quantum mechanical/machine learning potential correction (QM/Δ-MLP) that uses… read more here.
Keywords: drug discovery; drug; model drug; quantum deep ... See more keywords
Microneedle ocular patch: fabrication, characterization, and ex-vivo evaluation using pilocarpine as model drug
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2020.1776317
Abstract: Abstract Context: Enhacing the ocular bioavailability of drugs after their topical application is a challenge. Objective: The objective of the study was to design, fabricate, and investigate the effectiveness of microneedle ocular patch (MOP) in… read more here.
Keywords: microneedle ocular; patch; drug; model drug ... See more keywords
Preparation and Evaluation of Ternary Polymeric Blends for Controlled Release Matrices Containing Weakly Basic Model Drug.
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DOI: 10.2174/1567201817666200731170040
Abstract: OBJECTIVE The objective of this study was to evaluate the suitability of ternary mixture of smart polymers comprised of Eudragit®E100, Eudragit®L100, and sodium alginate to serve as a carrier for sustained drug release for weakly… read more here.
Keywords: controlled release; release; drug; model drug ... See more keywords
Chicken embryo: a useful animal model for drug testing?
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202207_29208
Abstract: The use of chicken embryos (CEs) as an in vivo experimental model for different pharmaceutical purposes is not a novelty. However, in recent years, the number of reports employing CE to evaluate several parameters, such… read more here.
Keywords: embryo useful; chicken embryo; model drug; model ... See more keywords
Bioluminescent Zebrafish Transplantation Model for Drug Discovery
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.893655
Abstract: In the last decade, zebrafish have accompanied the mouse as a robust animal model for cancer research. The possibility of screening small-molecule inhibitors in a large number of zebrafish embryos makes this model particularly valuable.… read more here.
Keywords: drug discovery; bioluminescent zebrafish; model drug; drug ... See more keywords
Synthesis of Saponite Based Nanocomposites to Improve the Controlled Oral Drug Release of Model Drug Quinine Hydrochloride Dihydrate.
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceuticals"
DOI: 10.3390/ph12030105
Abstract: In the present research study, a 2:1 type of smectite clay minerals, namely natural saponite (NSAP) and synthetic saponite (SSAP), was demonstrated for the first time to be controlled drug release host materials for the… read more here.
Keywords: model drug; drug; drug release; release ... See more keywords