A Self‐Assembled Binary Protein Model Explains High‐Performance Salivary Lubrication from Macro to Nanoscale
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.201901549
Abstract: Salivary pellicle, a spontaneously formed, intricate architecture in the human oral cavity, is a high‐performance bio‐lubricant that coats and protects biological surfaces with varying elastic modulus against frictional damage. Although salivary lubrication underpins the fundamentals… read more here.
Keywords: lubrication; model; salivary lubrication; macro nanoscale ... See more keywords
A simple model explains the cell cycle-dependent assembly of centromeric nucleosomes in holocentric species
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab648
Abstract: Abstract Centromeres are essential for chromosome movement. In independent taxa, species with holocentric chromosomes exist. In contrast to monocentric species, where no obvious dispersion of centromeres occurs during interphase, the organization of holocentromeres differs between… read more here.
Keywords: explains cell; holocentric species; cell cycle; centromeric nucleosomes ... See more keywords
A multi-scale model explains oscillatory slowing and neuronal hyperactivity in Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2022.0607
Abstract: Alzheimer’s disease is the most common cause of dementia and is linked to the spreading of pathological amyloid-β and tau proteins throughout the brain. Recent studies have highlighted stark differences in how amyloid-β and tau… read more here.
Keywords: alzheimer disease; slowing neuronal; model explains; amyloid tau ... See more keywords
Spindle Dynamics Model Explains Chromosome Loss Rates in Yeast Polyploid Cells
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00296
Abstract: Faithful chromosome segregation, driven by the mitotic spindle, is essential for organismal survival. Neopolyploid cells from diverse species exhibit a significant increase in mitotic errors relative to their diploid progenitors, resulting in chromosome nondisjunction. In… read more here.
Keywords: chromosome loss; dynamics model; spindle dynamics; model ... See more keywords