A continuous‐infusion dynamic MRI model at 3.0 Tesla for the serial quantitative evaluation of microvascular proliferation in an animal model of glioblastoma multiforme
Sign Up to like & getrecommendations! Published in 2017 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.26591
Abstract: To develop a continuous‐infusion dynamic MRI technique to characterize tumor‐associated microvascular proliferation (MVP) in a rat brain model of glioblastoma multiforme. read more here.
Keywords: continuous infusion; infusion dynamic; model glioblastoma; microvascular proliferation ... See more keywords
A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-019-03107-0
Abstract: PurposeGlioblastoma (GBM) is the most common invasive malignant brain tumour in adults. It is traditionally investigated in vitro by culturing cells as a monolayer (2D culture) or as neurospheres (clusters enriched in cancer stem cells)… read more here.
Keywords: vitro model; novel vitro; model glioblastoma; model ... See more keywords
New approaches to model glioblastoma in vitro using brain organoids: implications for precision oncology
Sign Up to like & getrecommendations! Published in 2019 at "Translational cancer research"
DOI: 10.21037/tcr.2019.09.08
Abstract: Glioblastoma is an aggressive form of primary brain cancer for which new treatment approaches are desperately needed. To achieve this goal, better experimental approaches to study human glioblastoma are required; and in particular, methods that… read more here.
Keywords: approaches model; glioblastoma vitro; new approaches; model glioblastoma ... See more keywords
An Orthotopic Model of Glioblastoma Is Resistant to Radiodynamic Therapy with 5-AminoLevulinic Acid
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DOI: 10.3390/cancers14174244
Abstract: Simple Summary Radiosensitization of glioblastoma is a major ambition to increase the survival of this incurable cancer. Before surgery, oral administration of 5-aminolevulinic acid leads to the accumulation of fluorescent protoporphyrin IX, preferentially in the… read more here.
Keywords: radiosensitization; glioblastoma; aminolevulinic acid; model glioblastoma ... See more keywords