Bleomycin‐induced lung injury: Revisiting an old tool to model group III PH associated with pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12177
Abstract: Abstract Pulmonary hypertension (PH) is a chronic disorder of the pulmonary circulation that often associates with other respiratory diseases (i.e., group III PH), leading to worsened symptoms and prognosis, notably when combined with interstitial lung… read more here.
Keywords: model group; pulmonary fibrosis; group iii; iii associated ... See more keywords
Therapeutic Effect of Ershen Pill (二神丸) Extract on Pi (Spleen)-Shen (Kidney) Yang Deficiency-Induced Diarrhea in Rat Model
Sign Up to like & getrecommendations! Published in 2018 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-017-2766-4
Abstract: ObjectiveTo investigate whether Ershen Pill (ESP, 二神丸) could alleviate the symptom of Pi (Spleen)-Shen (Kidney) yang deficiency (PSYD)-induced diarrhea in rat model and explore its anti-diarrhea mechanism.MethodsSeventy-five Sprague-Dawley rats were divided into 5 groups by… read more here.
Keywords: group; induced diarrhea; model; model group ... See more keywords
Effect of moxibustion on VEGF and EGF expressions in tumor tissues of rats with gastric tumor
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Acupuncture and Tuina Science"
DOI: 10.1007/s11726-019-1106-y
Abstract: ObjectiveTo explore the inhibitory effect of moxibustion on tumor growth and metastasis, and also its possible mechanism, in gastric tumor-bearing rats by investigating the expressions of vascular endothelial growth factor (VEGF) and epidermal growth factor… read more here.
Keywords: moxibustion; vegf egf; group; model group ... See more keywords
Cortical remodeling after electroacupuncture therapy in peripheral nerve repairing model
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.04.009
Abstract: Electroacupuncture (EA) is an alternative therapy for peripheral nerve injury (PNI). The treatment relies on post-therapeutic effect rather than real-time effect. We utilized fMRI to clarify the resting-state alteration caused by sustained effect of EA… read more here.
Keywords: group; nerve repairing; model group; nerve ... See more keywords
miR-125 regulates PI3K/Akt/mTOR signaling pathway in rheumatoid arthritis rats via PARP2
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20180890
Abstract: The present study aimed to explore miR-125 effects on rheumatoid arthritis (RA) development to provide a potential target for RA. Briefly, rat RA model was established (Model group) by injection of Freund’s Complete Adjuvant into… read more here.
Keywords: parp2; mir 125; pi3k akt; group ... See more keywords
Ketamine delays progression of oxidative and damaged cataract through regulating HMGB-1/NF-κB in lens epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2018.1478851
Abstract: Abstract Objective: Lens epithelial cell (LEC) membrane damage is one of the pathogenesis of cataract. High mobility group box-1 (HMGB-1) and nuclear factor-κB (NF-κB) play vital roles in a variety of diseases, such as inflammation.… read more here.
Keywords: lens epithelial; group; model group; cataract ... See more keywords
The Protective Effect of Aspirin against Myocardial Hypertrophy in Rats
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/2043415
Abstract: The protective effect of aspirin against myocardial hypertrophy (MH) was studied. Model rats of pressure overload MH were prepared by abdominal aortic coarctation. Rats were randomly divided into the sham group (n = 9), MH… read more here.
Keywords: week; protective effect; group; model ... See more keywords
Pramipexole Inhibits Neuronal Apoptosis in Rats with Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/7002630
Abstract: To explore the inhibition of pramipexole on the neuronal apoptosis and its influences on the expressions of brain tissue brain-derived neurotrophic factor (BDNF), and serum miR-103a and miR-30b and inflammatory factors in rats with Parkinson's… read more here.
Keywords: model group; group; model; normal group ... See more keywords
The Effect and Mechanism of New Processing Method of Codonopsis pilosula on Endocrine Physique Index in Rats
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/7703612
Abstract: Objective To explore the effect and mechanism of a new processing method of Codonopsis pilosula (CP) on the endocrine physique index in rats. Methods The rats were randomly assigned into the control group, model group,… read more here.
Keywords: honey; moxibustion group; model group; group ... See more keywords
Effect of Diammonium Glycyrrhizinate in Improving Focal Cerebral Ischemia-Reperfusion Injury in Rats Through Multiple Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Dose-Response"
DOI: 10.1177/15593258221142792
Abstract: Objective Acute ischemic stroke is a current major disabling and killer disease worldwide. We aimed to investigate the protective effect and mechanism of diammonium glycyrrhizinate in alleviating acute ischemic stroke. Methods Ninety male Sprague Dawley… read more here.
Keywords: positive cells; nissl bodies; model group; group ... See more keywords
SIRT1 regulates hypoxia-induced oxidative stress in cardiomyocytes via PI3K/MTOR signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.2.7
Abstract: This work was developed to investigate the activation of silent information regulator 1 (SIRT1) to regulate hypoxia-induced oxidative stress in cardiomyocytes through the PI3K/MTOR signaling pathway. For this purpose, 30 SD healthy rats were selected,… read more here.
Keywords: group compared; mtor; model group; group ... See more keywords