Betahistine prevents development of endolymphatic hydrops in a mouse model of insulin resistance and diabetes
Sign Up to like & getrecommendations! Published in 2023 at "Acta Oto-Laryngologica"
DOI: 10.1080/00016489.2023.2171116
Abstract: Abstract Background Diabetes is associated with inner ear dysfunction. Furthermore, C57BL/6J mice fed high fat diet (HFD), a model for insulin resistance and diabetes, develop endolymphatic hydrops (EH). Aim Evaluate if betahistine, spironolactone (aldosterone antagonist)… read more here.
Keywords: insulin resistance; betahistine; resistance diabetes; model insulin ... See more keywords
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Systems Biology"
DOI: 10.15252/msb.20209684
Abstract: To elucidate the contributions of specific lipid species to metabolic traits, we integrated global hepatic lipid data with other omics measures and genetic data from a cohort of about 100 diverse inbred strains of mice… read more here.
Keywords: regulation liver; liver lipids; lipids mouse; genetic regulation ... See more keywords