ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis
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DOI: 10.1038/s41598-017-07340-3
Abstract: Von Willebrand factor (VWF) is secreted as an acute phase protein during inflammation. ADAMTS-13 regulates the size and prothrombotic activity of VWF by it’s specific proteolytic activity. To determine the relevance of this regulatory pathway… read more here.
Keywords: model invasive; invasive pulmonary; mice; adamts ... See more keywords
SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.1207
Abstract: Abstract Background Azoles are the most common anti-fungal agents for the treatment of Aspergillus infections. Echinocandins have demonstrated utility in Aspergillus infections, but are limited in use due to a lack of oral bioavailability. SCY-078… read more here.
Keywords: model invasive; murine model; invasive aspergillosis; scy 078 ... See more keywords
A Multimodal Imaging Approach Enables In Vivo Assessment of Antifungal Treatment in a Mouse Model of Invasive Pulmonary Aspergillosis
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00240-18
Abstract: ABSTRACT Aspergillus fumigatus causes life-threatening lung infections in immunocompromised patients. Mouse models are extensively used in research to assess the in vivo efficacies of antifungals. In recent years, there has been an increasing interest in… read more here.
Keywords: treatment; model invasive; multimodal imaging; invasive pulmonary ... See more keywords