Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP
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DOI: 10.1182/bloodadvances.2023012155
Abstract: Key Points • Human FcγRIII monovalent blocking as a 1-armed antibody or albumin fusion protein are effective in a humanized model of ITP.• The monovalent albumin fusion protein showed no AEs, whereas the Fc-impaired 1-armed… read more here.
Keywords: model itp; receptor iiia; gamma receptor; human gamma ... See more keywords