A mechanobiological mathematical model of liver metabolism.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.27451
Abstract: The liver plays a complex role in metabolism and detoxification, and better tools are needed to understand its function and to develop liver-targeted therapies. In this study, we establish a mechanobiological model of liver transport… read more here.
Keywords: liver metabolism; metabolism; rheology; model liver ... See more keywords
Electric model of liver tissue for investigation of electrosurgical impacts
Sign Up to like & getrecommendations! Published in 2017 at "Electrical Engineering"
DOI: 10.1007/s00202-017-0625-0
Abstract: In this paper, the method of human organ (liver tissue) modelling in the COMSOL environment is presented. Mentioned problems are motivated by the occurrence of negative events during operations utilizing electrosurgery in the tissues with… read more here.
Keywords: electric model; liver tissue; tissue; model liver ... See more keywords
Development and validation of a primate model for liver fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2019.106600
Abstract: INTRODUCTION Many liver diseases involve liver fibrosis. Most preclinical studies of liver fibrosis are carried out in small animals such as rodents, and thus lack direct potential for extrapolation to human diseases. The aim of… read more here.
Keywords: model liver; primate model; fibrosis; liver fibrosis ... See more keywords
A novel mouse model for liver metastasis of prostate cancer reveals dynamic tumour‐immune cell communication
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DOI: 10.1111/cpr.13056
Abstract: In contrast to extensive studies on bone metastasis in advanced prostate cancer (PCa), liver metastasis has been under‐researched so far. In order to decipher molecular and cellular mechanisms underpinning liver metastasis of advanced PCa, we… read more here.
Keywords: prostate cancer; metastasis; model liver; liver metastasis ... See more keywords
Calibration of an Electrical Analog Model of Liver Hemodynamics in Fontan Patients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4049075
Abstract: Fontan associated liver disease is a common complication in patients with Fontan circulation, who were born with a single functioning heart ventricle. The hepatic venous pressure gradient (HVPG) is used to assess liver health and… read more here.
Keywords: liver; model liver; fontan patients; hemodynamics ... See more keywords
Antifibrotic Effect of Marine Ovothiol in an In Vivo Model of Liver Fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/5045734
Abstract: Liver fibrosis is a complex process caused by chronic hepatic injury, which leads to an excessive increase in extracellular matrix protein accumulation and fibrogenesis. Several natural products, including sulfur-containing compounds, have been investigated for their… read more here.
Keywords: model liver; antifibrotic effect; fibrosis; liver fibrosis ... See more keywords
Effects of Combined Admistration of Imatinib and Sorafenib in a Murine Model of Liver Fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25184310
Abstract: Liver fibrosis is defined as excessive extracellular matrix deposition in the hepatic parenchyma as a consequence of complex interactions among matrix-producing hepatic stellate cells (HSCs) and liver-resident and infiltrating cells. In addition to the liver,… read more here.
Keywords: model liver; imatinib sorafenib; fibrosis; liver fibrosis ... See more keywords