TLR7 Activation Accelerates Cardiovascular Pathology in a Mouse Model of Lupus
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DOI: 10.3389/fimmu.2022.914468
Abstract: We report a novel model of lupus-associated cardiovascular pathology accelerated by the TLR7 agonist R848 in lupus-prone B6.Sle1.Sle2.Sle3 (TC) mice. R848-treated TC mice but not non-autoimmune C57BL/6 (B6) controls developed microvascular inflammation and myocytolysis with… read more here.
Keywords: model lupus; cardiovascular pathology; pathology; mice ... See more keywords