Efficacy of folic acid as an adjunct to lithium therapy on manic-like behaviors, oxidative stress and inflammatory parameters in an animal model of mania
Sign Up to like & getrecommendations! Published in 2019 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-019-00503-3
Abstract: Evaluate the efficacy of folic acid (FA) as a therapeutic adjunct to lithium (Li) on the manic-like behaviors as well as parameters of oxidative stress and inflammation in an animal model of mania induced by… read more here.
Keywords: inflammatory parameters; manic like; like behaviors; model mania ... See more keywords
Inhibition of GSK-3β on Behavioral Changes and Oxidative Stress in an Animal Model of Mania
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1226-2
Abstract: AbstractThe present study evaluated the effects of AR-A014418 on behavioral and oxidative stress parameters of rats submitted to the animal model of mania induced by ouabain (OUA). Wistar rats were submitted to stereotaxic surgery and… read more here.
Keywords: model mania; stress; animal model; oxidative stress ... See more keywords
Effects of lithium and valproate on behavioral parameters and neurotrophic factor levels in an animal model of mania induced by paradoxical sleep deprivation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2019.09.003
Abstract: The present study aimed to evaluate the effects of treatment with lithium (Li) and valproate (VPA) on behaviors and brain BDNF, NGF, NT-3, NT-4 and GDNF levels in mice submitted to paradoxical sleep deprivation (PSD),… read more here.
Keywords: sleep deprivation; animal model; model mania; psd ... See more keywords
Blackberry extract improves behavioral and neurochemical dysfunctions in a ketamine-induced rat model of mania
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DOI: 10.1016/j.neulet.2019.134566
Abstract: Bipolar disorder is a chronic mood disorder characterized by episodes of mania and depression. The aim of this study was to investigate the effects of blackberry extract on behavioral parameters, oxidative stress and inflammatory markers… read more here.
Keywords: ketamine induced; cerebral cortex; blackberry extract; model mania ... See more keywords
Cognitive flexibility impairment and reduced frontal cortex BDNF expression in the ouabain model of mania
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DOI: 10.1016/j.neuroscience.2016.05.058
Abstract: Central infusion of the Na+/K+-ATPase inhibitor, ouabain in rats serves as an animal model of mania because it leads to hyperactivity, as well as reproduces ion dysregulation and reduced brain-derived neurotrophic factor (BDNF) levels similar… read more here.
Keywords: model mania; cognitive flexibility; ouabain; frontal cortex ... See more keywords