Comparison of Synthetic Neuronal Model Membrane Mimics in Amyloid Aggregation at Atomic Resolution.
Sign Up to like & getrecommendations! Published in 2020 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.0c00166
Abstract: Alzheimer's disease (AD) is a severe neurodegenerative disorder caused by abnormal accumulation of toxic amyloid plaques of the amyloid-beta (Aβ) or the tau proteins in the brain. The plaque deposition leading to the collapse of… read more here.
Keywords: membrane; amyloid aggregation; model membrane; bbb ... See more keywords
Biomembrane Permeabilization: Statistics of Individual Leakage Events Harmonize the Interpretation of Vesicle Leakage.
Sign Up to like & getrecommendations! Published in 2018 at "ACS nano"
DOI: 10.1021/acsnano.7b08184
Abstract: The mode of action of membrane-active molecules, such as antimicrobial, anticancer, cell penetrating, and fusion peptides and their synthetic mimics, transfection agents, drug permeation enhancers, and biological signaling molecules (e.g., quorum sensing), involves either the… read more here.
Keywords: interpretation; biomembrane permeabilization; leakage; model membrane ... See more keywords
Giant Endoplasmic Reticulum vesicles (GERVs), a novel model membrane tool
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-59700-1
Abstract: Artificial giant vesicles have proven highly useful as membrane models in a large variety of biophysical and biochemical studies. They feature accessibility for manipulation and detection, but lack the compositional complexity needed to reconstitute complicated… read more here.
Keywords: tool; membrane; model membrane; endoplasmic reticulum ... See more keywords
Theoretical model of membrane protrusions driven by curved active proteins
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.1101/2023.01.31.526240
Abstract: Eukaryotic cells intrinsically change their shape, by changing the composition of their membrane and by restructuring their underlying cytoskeleton. We present here further studies and extensions of a minimal physical model, describing a closed vesicle… read more here.
Keywords: membrane protrusions; protrusions driven; model membrane; model ... See more keywords
Interactions of Truncated Menaquinones in Lipid Monolayers and Bilayers
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22189755
Abstract: Menaquinones (MK) are hydrophobic molecules that consist of a naphthoquinone headgroup and a repeating isoprenyl side chain and are cofactors used in bacterial electron transport systems to generate cellular energy. We have previously demonstrated that… read more here.
Keywords: truncated menaquinones; truncated mks; interactions truncated; truncated homologues ... See more keywords