Articles with "model membranes" as a keyword



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Studying the TRAF2 binding to model membranes: The role of subunits dissociation

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Published in 2018 at "Biotechnology and Applied Biochemistry"

DOI: 10.1002/bab.1615

Abstract: The ability of a C‐terminal truncated form of TRAF2 to bind synthetic vesicles has been quantitatively studied by steady‐state fluorescence energy transfer from the protein to large unilamellar vesicles (LUVs) prepared with different lipid mixtures.… read more here.

Keywords: studying traf2; traf2 binding; dissociation; binding model ... See more keywords
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Comparing activity, toxicity and model membrane interactions of Jelleine-I and Trp/Arg analogs: analysis of peptide aggregation

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Published in 2020 at "Amino Acids"

DOI: 10.1007/s00726-020-02847-y

Abstract: Increasing resistance in antibiotic and chemotherapeutic treatments has been pushing studies of design and evaluation of bioactive peptides. Designing relies on different approaches from minimalist sequences and endogenous peptides modifications to computational libraries. Evaluation relies… read more here.

Keywords: aggregation; toxicity; model membranes; membrane interactions ... See more keywords
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Incorporation of cyclodiene pesticides and their polar metabolites to model membranes of soil bacteria

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Published in 2020 at "Journal of Molecular Liquids"

DOI: 10.1016/j.molliq.2019.112019

Abstract: Abstract The world-wide application of cyclodiene pesticides (CP) lead to severe pollution of arable land and because of the long half-lives they will be for many decades present in the soil. The only reasonable way… read more here.

Keywords: polar metabolites; model membranes; metabolites model; membrane ... See more keywords
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Molecular Basis for Membrane Selectivity of Antimicrobial Peptide Pleurocidin in the Presence of Different Eukaryotic and Prokaryotic Model Membranes

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Published in 2019 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.9b00245

Abstract: Pleurocidin, a 25-residue cationic peptide, has antimicrobial activity against bacteria and fungi but exhibits very low hemolytic activity against human red blood cells (RBC). The peptide inserts into the bacterial membrane and causes the membrane… read more here.

Keywords: basis membrane; molecular basis; pleurocidin; model membranes ... See more keywords
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A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation

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Published in 2022 at "ACS Chemical Neuroscience"

DOI: 10.1021/acschemneuro.2c00765

Abstract: The aggregation of the amyloid β (Aβ) peptide is one of the molecular hallmarks of Alzheimer’s disease (AD). Although Aβ deposits have mostly been observed extracellularly, various studies have also reported the presence of intracellular… read more here.

Keywords: map influence; model membranes; aggregation; kinetic map ... See more keywords
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Phase Separation in Atomistic Simulations of Model Membranes.

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Published in 2020 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.9b11057

Abstract: Understanding the lateral organization in plasma membranes remains an open problem despite a large body of research. Model membranes with coexisting micron-size domains are routinely employed as simplified models of plasma membranes. Many molecular dynamics… read more here.

Keywords: phase separation; phase; cholesterol; model membranes ... See more keywords
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A disordered tether to iLID improves photoswitchable protein patterning on model membranes.

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Published in 2023 at "Chemical communications"

DOI: 10.1039/d3cc00709j

Abstract: Reversible protein patterning on model membranes is important to reproduce spatiotemporal protein dynamics in vitro. An engineered version of iLID, disiLID, with a disordered domain as a membrane tether improves the recruitment of Nano under… read more here.

Keywords: protein patterning; model membranes; protein; patterning model ... See more keywords
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Model Membranes and Antimicrobial Activities of pH-Sensitive Copolymers

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Published in 2023 at "Journal of the Brazilian Chemical Society"

DOI: 10.21577/0103-5053.20230079

Abstract: Polymers are options as antimicrobials for skin protection, antifouling surfaces, and fabrics. Here we analyzed the interaction of polymers based on poly(methacrylate) (PMMA) and poly((dimethylamino ethyl) methacrylate) (PDMAEMA) with model membranes and bacteria. We used… read more here.

Keywords: sensitive copolymers; membranes antimicrobial; model membranes; antimicrobial activities ... See more keywords
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Studies on the Interaction of Alyteserin 1c Peptide and Its Cationic Analogue with Model Membranes Imitating Mammalian and Bacterial Membranes

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Published in 2019 at "Biomolecules"

DOI: 10.3390/biom9100527

Abstract: Antimicrobial peptides (AMPs) are effector molecules of the innate immune system and have been isolated from multiple organisms. Their antimicrobial properties are due to the fact that they interact mainly with the anionic membrane of… read more here.

Keywords: peptide; analogue; model membranes; studies interaction ... See more keywords
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Effect of Distigmasterol-Modified Acylglycerols on the Fluidity and Phase Transition of Lipid Model Membranes

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Published in 2022 at "Membranes"

DOI: 10.3390/membranes12111054

Abstract: Plant sterols are known for their health-promoting effects, lowering blood cholesterol levels and alleviating cardiovascular disease. In this work, we continue our research on the asymmetric acylglycerols in which fatty acid residues are replaced by… read more here.

Keywords: effect; phase transition; model membranes; modified acylglycerols ... See more keywords
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Impact of Pollutant Ozone on the Biophysical Properties of Tear Film Lipid Layer Model Membranes

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Published in 2023 at "Membranes"

DOI: 10.3390/membranes13020165

Abstract: Ozone exposure from environmental smog has been implicated as a risk factor for developing dry eye disease (DED). The tear film lipid layer (TFLL), which is the outermost layer of the tear film and responsible… read more here.

Keywords: model membranes; layer; ozone; tear film ... See more keywords