The vaginal distention model in mice is not a reliable model of simulated birth trauma‐induced stress urinary incontinence
Sign Up to like & getrecommendations! Published in 2019 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.23886
Abstract: Vaginal distention (VD) is a validated model of birth‐related trauma in rats. Recently a mouse VD model was reported. Our study was originally conducted to evaluate the impact of age on VD in mice. This… read more here.
Keywords: model mice; model; distention model; vaginal distention ... See more keywords
Functional role of natural killer T cells in non-obese pre-diabetes model mice
Sign Up to like & getrecommendations! Published in 2017 at "Cytotechnology"
DOI: 10.1007/s10616-017-0157-5
Abstract: Pre-diabetic patients have a high risk of developing diabetes as well as other associated diseases. From the viewpoint of risk assessment and to assist the development of protective therapies, we focused on the functional role… read more here.
Keywords: pre diabetes; diabetes model; model mice; role natural ... See more keywords
Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer’s disease model mice
Sign Up to like & getrecommendations! Published in 2021 at "Current Biology"
DOI: 10.1016/j.cub.2021.05.039
Abstract: Not much is known about how the dentate gyrus (DG) and hippocampal CA3 networks, critical for memory and spatial processing, malfunction in Alzheimer's disease (AD). While studies of associative memory deficits in AD have focused… read more here.
Keywords: alzheimer disease; fad; model mice; mice ... See more keywords
Pathophysiological role of prostaglandin E2-induced up-regulation of the EP2 receptor in motor neuron-like NSC-34 cells and lumbar motor neurons in ALS model mice
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2017.06.013
Abstract: ABSTRACT Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective degeneration of motor neurons. The primary triggers for motor neuronal death are still unknown, but inflammation is considered to be an important… read more here.
Keywords: model mice; motor neurons; als model; motor neuron ... See more keywords
Effects of total flavonoids of raspberry on perimenopausal model in mice
Sign Up to like & getrecommendations! Published in 2018 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2017.08.009
Abstract: To study the effect of raspberry total flavonoids on perimenopausal model in mice. Blank group, sham operation, and the rest of the mice made the menopausal model. Choose 72 mice castrated completely random divided into… read more here.
Keywords: model mice; group; mice; total flavonoids ... See more keywords
Hyper BOLD Activation in Dorsal Raphe Nucleus of APP/PS1 Alzheimer’s Disease Mouse during Reward-Oriented Drinking Test under Thirsty Conditions
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-60894-7
Abstract: Alzheimer’s disease (AD), a neurodegenerative disease, causes behavioural abnormalities such as disinhibition, impulsivity, and hyperphagia. Preclinical studies using AD model mice have investigated these phenotypes by measuring brain activity in awake, behaving mice. In this… read more here.
Keywords: brain activity; model mice; alzheimer disease; thirsty conditions ... See more keywords
Alterations in the autonomic nerve activities of prenatal autism model mice treated with valproic acid at different developmental stages
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-74662-0
Abstract: Autism spectrum disorder (ASD) is characterized by impairment of social communication, repetitive behavior and restrictive interest. The risk of ASD is strongly associated with the prenatal period; for instance, the administration of valproic acid (VPA)… read more here.
Keywords: autonomic nervous; model mice; valproic acid; model ... See more keywords
Relationships of pain-causing substances with dry skin and effects of zaltoprofen on alleviation of symptoms in arthritis model mice
Sign Up to like & getrecommendations! Published in 2022 at "Cutaneous and Ocular Toxicology"
DOI: 10.1080/15569527.2022.2127749
Abstract: Abstract Purpose: Skin dryness is a symptom of rheumatoid arthritis (RA). However, the mechanisms through which dry skin is induced in RA are unclear. Accordingly, in this study, we characterized substances related to pruritus and… read more here.
Keywords: model mice; arthritis model; skin; dry skin ... See more keywords
A combinatorial approach increases SMN level in SMA model mice.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac068
Abstract: Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by reduced expression of the survival motor neuron (SMN) protein. Current disease-modifying therapies increase SMN levels and dramatically improve survival and motor function of SMA patients.… read more here.
Keywords: model mice; sma; increases smn;
Enhancing sleep after training improves memory in down syndrome model mice.
Sign Up to like & getrecommendations! Published in 2022 at "Sleep"
DOI: 10.1093/sleep/zsab247
Abstract: Down syndrome (DS) is a genetic disorder caused by the presence of all or part of the third copy of chromosome 21. DS is associated with cognitive disabilities, for which there are no drug therapies.… read more here.
Keywords: model mice; training; enhancing sleep; model ... See more keywords
A New Face Subunit Transplant Model in Mice, Containing Skin, Mandible, and Oral Mucosa for Future Face Vascularized Composite Allotransplantation Studies.
Sign Up to like & getrecommendations! Published in 2019 at "Plastic and reconstructive surgery"
DOI: 10.1097/prs.0000000000005774
Abstract: BACKGROUND In immunologic research, mice have advantages over other animals, such as low costs, easy handling, suitable life cycle, and adequate laboratory resources. However, vascularized composite allotransplantation surgery using mice is not popular, partly because… read more here.
Keywords: oral mucosa; mice; face; model mice ... See more keywords