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   Articles with "model mice" as a keyword



Exploring gastroprotective effect and mechanisms of epigallocatechin gallate‐impregnated black garlic in acidic ethanol‐induced gastric ulcer model mice

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recommendations! Published in 2025 at "Journal of the Science of Food and Agriculture"

DOI: 10.1002/jsfa.70109

Abstract: Peptic ulcers, particularly gastric ulcers (GUs), are multifactorial disorders with unclear mechanisms. Black garlic (BG) has shown gastroprotective effects. This study evaluated the effects of BG and epigallocatechin gallate‐impregnated BG (EG) in acidic ethanol (AE)‐induced… read more here.

Keywords: ethanol induced; model mice; acidic ethanol; gallate impregnated ... See more keywords

The vaginal distention model in mice is not a reliable model of simulated birth trauma‐induced stress urinary incontinence

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recommendations! Published in 2019 at "Neurourology and Urodynamics"

DOI: 10.1002/nau.23886

Abstract: Vaginal distention (VD) is a validated model of birth‐related trauma in rats. Recently a mouse VD model was reported. Our study was originally conducted to evaluate the impact of age on VD in mice. This… read more here.

Keywords: model mice; model; distention model; vaginal distention ... See more keywords

Minimal invasive open tibial fracture model in mice

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recommendations! Published in 2025 at "International Orthopaedics"

DOI: 10.1007/s00264-025-06644-8

Abstract: Fracture models in animals are essential to analyze bone healing in musculoskeletal research fields. Especially in small animals, fractures are difficult to simulate and stabilize. Therefore, a fracture model is desirable with a short operation… read more here.

Keywords: fracture; model mice; model; open tibial ... See more keywords

Functional role of natural killer T cells in non-obese pre-diabetes model mice

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recommendations! Published in 2017 at "Cytotechnology"

DOI: 10.1007/s10616-017-0157-5

Abstract: Pre-diabetic patients have a high risk of developing diabetes as well as other associated diseases. From the viewpoint of risk assessment and to assist the development of protective therapies, we focused on the functional role… read more here.

Keywords: pre diabetes; diabetes model; model mice; role natural ... See more keywords
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Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer’s disease model mice

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recommendations! Published in 2021 at "Current Biology"

DOI: 10.1016/j.cub.2021.05.039

Abstract: Not much is known about how the dentate gyrus (DG) and hippocampal CA3 networks, critical for memory and spatial processing, malfunction in Alzheimer's disease (AD). While studies of associative memory deficits in AD have focused… read more here.

Keywords: alzheimer disease; fad; model mice; mice ... See more keywords

Pathophysiological role of prostaglandin E2-induced up-regulation of the EP2 receptor in motor neuron-like NSC-34 cells and lumbar motor neurons in ALS model mice

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recommendations! Published in 2018 at "Neurochemistry International"

DOI: 10.1016/j.neuint.2017.06.013

Abstract: ABSTRACT Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective degeneration of motor neurons. The primary triggers for motor neuronal death are still unknown, but inflammation is considered to be an important… read more here.

Keywords: model mice; motor neurons; als model; motor neuron ... See more keywords

Effects of total flavonoids of raspberry on perimenopausal model in mice

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recommendations! Published in 2018 at "Saudi Journal of Biological Sciences"

DOI: 10.1016/j.sjbs.2017.08.009

Abstract: To study the effect of raspberry total flavonoids on perimenopausal model in mice. Blank group, sham operation, and the rest of the mice made the menopausal model. Choose 72 mice castrated completely random divided into… read more here.

Keywords: model mice; group; mice; total flavonoids ... See more keywords

Atypical cortical feedback underlies failure to process contextual information in the superior colliculus of Scn2a+/− autism model mice

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-63788-2

Abstract: Atypical sensory integration and contextual learning are common symptoms in autism spectrum disorder (ASD), but how sensory circuits are affected remains elusive. Here we focused on the early visual information processing, and performed in vivo… read more here.

Keywords: information; model mice; modulation; superior colliculus ... See more keywords
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Hyper BOLD Activation in Dorsal Raphe Nucleus of APP/PS1 Alzheimer’s Disease Mouse during Reward-Oriented Drinking Test under Thirsty Conditions

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-60894-7

Abstract: Alzheimer’s disease (AD), a neurodegenerative disease, causes behavioural abnormalities such as disinhibition, impulsivity, and hyperphagia. Preclinical studies using AD model mice have investigated these phenotypes by measuring brain activity in awake, behaving mice. In this… read more here.

Keywords: brain activity; model mice; alzheimer disease; thirsty conditions ... See more keywords
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Alterations in the autonomic nerve activities of prenatal autism model mice treated with valproic acid at different developmental stages

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-74662-0

Abstract: Autism spectrum disorder (ASD) is characterized by impairment of social communication, repetitive behavior and restrictive interest. The risk of ASD is strongly associated with the prenatal period; for instance, the administration of valproic acid (VPA)… read more here.

Keywords: autonomic nervous; model mice; valproic acid; model ... See more keywords

Relationships of pain-causing substances with dry skin and effects of zaltoprofen on alleviation of symptoms in arthritis model mice

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recommendations! Published in 2022 at "Cutaneous and Ocular Toxicology"

DOI: 10.1080/15569527.2022.2127749

Abstract: Abstract Purpose: Skin dryness is a symptom of rheumatoid arthritis (RA). However, the mechanisms through which dry skin is induced in RA are unclear. Accordingly, in this study, we characterized substances related to pruritus and… read more here.

Keywords: model mice; arthritis model; skin; dry skin ... See more keywords