Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma
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DOI: 10.1038/s41598-024-57286-6
Abstract: Mutations in myocilin (MYOC) are the leading known genetic cause of primary open-angle glaucoma, responsible for about 4% of all cases. Mutations in MYOC cause a gain-of-function phenotype in which mutant myocilin accumulates in the… read more here.
Keywords: model myocilin; myocilin; mouse model; cas9 ... See more keywords